Delivery Strategies, Structural Modification, and Pharmacological Mechanisms of Honokiol: A Comprehensive Review

C Pan, Q Li, S **ong, Y Yang, Y Yang… - Chemistry & …, 2024 - Wiley Online Library
Honokiol (HK) is a traditional Chinese herbal bioactive compound that originates mainly
from the Magnolia species, traditionally used to treat anxiety and stroke, as well as …

Biological Potential and Therapeutic Effectiveness of Phytoproduct 'Fargesin' in Medicine: Focus on the Potential of an Active Phytochemical of Magnolia fargesii

K Patel, DK Patel - Recent Advances in Inflammation & Allergy …, 2024 - benthamdirect.com
Flos Magnoliae is one of the important medicinal plants in different traditional medicine,
including Chinese herbal medicine. Lignans and neolignans, including tetrahydrofurofuran …

Honokiol and magnolol: A review of structure-activity relationships of their derivatives

SY Dai, WX Qin, S Yu, C Li, YH Yang, YH Pei - Phytochemistry, 2024 - Elsevier
Honokiol (HK) and magnolol (MAG) are typical representatives of neolignans possessing a
wide range of biological activities and are employed as traditional medicines in Asia. In the …

Recent advances of honokiol: pharmacological activities, manmade derivatives and structure-activity relationship

X Li, Z Yuan, Y Wang, W Wang, J Shi - European Journal of Medicinal …, 2024 - Elsevier
Honokiol (HNK) is a typical natural biphenyl polyphenol compound. It has been proven to
have a wide range of biological activities, including pharmacological effects such as anti …

[HTML][HTML] Synthesis of obovatol and related neolignan analogues as α-glucosidase and α-amylase inhibitors

C Sciacca, N Cardullo, L Pulvirenti, G Travagliante… - Bioorganic …, 2024 - Elsevier
Diabetes mellitus is a metabolic disease characterized by hyperglycemia, which can be
counteracted by the inhibition of α-glucosidase (α-Glu) and α-amylase (α-Amy), enzymes …

Flavonoids with lipase inhibitory activity from lemon squeezing waste: isolation, multispectroscopic and in silico studies

N Cardullo, D Calcagno, L Pulvirenti… - Journal of the …, 2024 - Wiley Online Library
BACKGROUND Obesity is recognized as a lifestyle‐related disease and the main risk factor
for a series of pathological conditions, including cardiovascular diseases, hypertension and …

Magnolol derivatives as specific and noncytotoxic inhibitors of breast cancer resistance protein (BCRP/ABCG2)

I da Silva Zanzarini, DH Kita, G Scheiffer… - Bioorganic …, 2024 - Elsevier
The breast cancer resistance protein (BCRP/ABCG2) transporter mediates the efflux of
numerous antineoplastic drugs, playing a central role in multidrug resistance related to …

Pancreatic lipase inhibitors as anti-obesity agents: a review of recent chemical scaffolds and their pancreatic lipase inhibitory potential

NA Mohsin, M Ahmad, M Farrukh, S Rafique - Medicinal Chemistry …, 2025 - Springer
Obesity is an excessive accumulation of fat in the body. The disease of obesity is increasing
all over the world. At present, only a few drugs are available for the treatment of obesity …

Discovery of natural anthraquinones as potent inhibitors against pancreatic lipase: structure-activity relationships and inhibitory mechanism

ZQ Chen, WY He, SY Yang, HH Ma, J Zhou… - Journal of Enzyme …, 2024 - Taylor & Francis
Obesity is acknowledged as a significant risk factor for various metabolic diseases, and the
inhibition of human pancreatic lipase (hPL) can impede lipid digestion and absorption …

The Potential of Magnolia spp. in the Production of Alternative Pest Control Substances

JV Hernandez-Rocha, SG Vásquez-Morales - Molecules, 2023 - mdpi.com
The irrational use of synthetic pesticides in agriculture has had negative impacts on
ecosystems and contributed to environmental pollution. Botanical pesticides offer a clean …