The impact of protein therapeutics in healthcare is steadily increasing, due to advancements
in the field of biotechnology and a deeper understanding of several pathologies. However …

In blood, the primary role of red blood cells (RBCs) is to transport oxygen via highly
regulated mechanisms involving hemoglobin (Hb). Hb is a tetrameric porphyrin protein …

Background Several circumstances such as accidents, surgery, traumatic hemorrhagic
shock, and other causalities cause major blood loss. Allogenic blood transfusion can be …

Blood transfusions, which usually consist in the administration of isolated red blood cells
(RBCs), are crucial in traumatic injuries, pre-surgical conditions and anemias. Although …

Transfusion of donor red blood cells (RBCs) is a crucial methodology required for the
treatment of acute trauma and anaemia or for surgical procedures. Due to the many …

Blood is a fluid connective tissue where living cells are suspended in noncellular liquid
matrix. The cellular components of blood render gas exchange (RBCs), immune …

There is an enormous demand for blood transfusions in daily clinical practices since blood
products, especially red blood cells (RBCs), can significantly improve survival. However …

In recent years, drug delivery has emerged as a more and more popular drug administration
means for the improvement of pharmacokinetics, minimization of side effects, and …

Blood transfusions are regarded as the most well-known and frequently performed cell
transplantations. Although current transfusion systems are sophisticated, they cannot be …

Hemoglobin (Hb)-loaded mesoporous silica nanoparticles (MSNs) coated with a lipid bilayer
(LB-MSNs) were investigated as an erythrocyte mimic. MSNs with a large average pore size …