Topical products, widely used to manage skin conditions, have evolved from simple potions
to sophisticated delivery systems. Their development has been facilitated by advances in …

This Review illustrates the evaluation of permeability of lipid membranes from molecular
dynamics (MD) simulation primarily using water and oxygen as examples. Membrane …

Hydrogels are ideal interfacing materials for on‐skin healthcare devices, yet their
susceptibility to dehydration hinders their practical use. While incorporating hygroscopic …

Breaching of the skin barrier is essential for delivering active pharmaceutical ingredients
(APIs) for pharmaceutical, dermatological and aesthetic applications. Chemical permeation …

Skin's effectiveness as a barrier to permeation of water and other chemicals rests almost
entirely in the outermost layer of the epidermis, the stratum corneum (SC), which consists of …

The use of methods at molecular scale for the discovery of new potential active ligands, as
well as previously unknown binding sites for target proteins, is now an established reality …

Lipid peroxidation by reactive oxygen species (ROS) during oxidative stress is non-
enzymatic damage that affects the integrity of biological membrane, and alters the fluidity …

Ethanol is widely used in various pharmaceutical and cosmetic formulations in order to
enhance skin penetration of active ingredients. While it is well known that ethanol partitions …

Lipid nanostructures such as solid lipid nanoparticles (SLNs) and nanostructured lipid
carriers (NLCs) significantly fetched the attention of scientific fraternity owing to lucrative …

Despite being widely used for basic and preclinical studies in dermatology, available animal
models only partly recapitulate human skin features, often leading to disappointing outputs …