Robotic thread-assisted clot removal for stroke treatment: A comprehensive review

K Sandhanam, D Rynjah, S Ghose, RK Sahu… - Neuroscience, 2025 - Elsevier
Stroke is the predominant factor of long-term impairment in developed nations and is a
major contributor to death globally. Stroke is a life-threatening neurological condition caused …

Recent developments in the design of functional derivatives of edaravone and exploration of their antioxidant activities

RD Mohan, NV Kulkarni - Molecular Diversity, 2024 - Springer
Edaravone, a pyrazalone derivative, is an antioxidant and free radical scavenger used to
treat oxidative stress-related diseases. It is a proven drug to mitigate conditions prevailing to …

Tetrahedral Framework Nucleic Acid-Based Delivery System for miRNA-124 and Stroke-Homing Peptide: Targeted Therapy for Acute Ischemic Stroke

G Du, Y Yao, W Chen, Y Lin, Y He… - ACS Applied Materials …, 2025 - ACS Publications
Acute ischemic stroke (AIS) is associated with a high mortality rate and poor prognosis, with
a lack of effective therapeutic drugs for post-thrombolytic treatment. MicroRNA-based gene …

Age affects the association of red blood cell indices with efficacy of remote ischemic conditioning in patients with acute moderate ischemic stroke

Q Wu, YN Zhang, NN Zhang, QY Liu, JR Cai… - Scientific Reports, 2024 - nature.com
We conducted a post hoc analysis of Remote Ischemic Conditioning for Acute Moderate
Ischemic Stroke (RICAMIS) to investigate whether red blood cell (RBC) indices are …

[PDF][PDF] The need for registry‐based studies in diabetes and stroke: a unique opportunity to understand whether diabetic treatments improve post‐stroke outcome

V Darsalia, E Vercalsteren, D Karampatsi… - Diabetes, Obesity and …, 2024 - researchgate.net
Therapies to improve outcomes after ischaemic stroke are currently exclusively based on
successful thrombolysis or thrombectomy. However, despite significant progress to extend …

Systematic review of neurological diseases and carbenoxolone: A double-edged sword?

Y Ikeuchi, M Kohta, K Hosoda, S Yamashita… - European Journal of …, 2025 - Elsevier
In this systematic review, we aim to clarify common findings on carbenoxolone's effects on
neurological conditions, including stroke, across studies and identify areas where …

A New Perspective on the Prediction and Treatment of Stroke: The Role of Uric Acid

B Zhu, X Huang, J Zhang, X Wang, S Tian, T Zhan… - Neuroscience …, 2024 - Springer
Stroke, a major cerebrovascular disease, has high morbidity and mortality. Effective methods
to reduce the risk and improve the prognosis are lacking. Currently, uric acid (UA) is …

[HTML][HTML] A novel anti-ischemic stroke candidate drug AAPB with dual effects of neuroprotection and cerebral blood flow improvement

J Wu, D Ji, W Jiao, J Jia, J Zhu, T Hang, X Chen… - … Pharmaceutica Sinica B, 2025 - Elsevier
Ischemic stroke (IS) is a globally life-threatening disease. Presently, few therapeutic
medicines are available for treating IS, and rt-PA is the only drug approved by the US Food …

The role of the cerebellum in anoxic–irschemic brain damage and neurological clinical trials

AM Sivalingam, A Pandian - Brain & Spine, 2024 - pmc.ncbi.nlm.nih.gov
The role of the cerebellum in anoxic–irschemic brain damage and neurological clinical trials
Page 1 Brain and Spine 4 (2024) 102865 Available online 10 July 2024 2772-5294/© 2024 …

Cerebrolysin, Hemorrhagic Transformation, and Anticoagulation Timing after Reperfusion Therapy in Stroke: Secondary Analysis of the CEREHETIS Trial

MN Kalinin, DR Khasanova - 2024 - researchsquare.com
Background Evidence supports Cerebrolysin's efficacy in reducing hemorrhagic
transformation (HT), but its impact on the timing of resuming anticoagulation therapy in …