Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Comparing the therapeutic potential of stem cells and their secretory products in regenerative medicine

JB Foo, QH Looi, PP Chong, NH Hassan… - Stem cells …, 2021 - Wiley Online Library
Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

Therapeutic applications of stem cell-derived exosomes

OAAY Abdulmalek, KH Husain, HKAA AlKhalifa… - International Journal of …, 2024 - mdpi.com
Exosomes are extracellular vesicles of endosomal origin, ranging from 30 to 150 nm in
diameter, that mediate intercellular transfer of various biomolecules, such as proteins, lipids …

Platelet‐rich plasma‐derived extracellular vesicles: A superior alternative in regenerative medicine?

J Wu, Y Piao, Q Liu, X Yang - Cell Proliferation, 2021 - Wiley Online Library
Abstract Platelet‐rich plasma (PRP), due to its promising therapeutic properties, has been
used in regenerative medicine for more than 30 years and numerous encouraging outcomes …

[HTML][HTML] Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction

Z Dai, C **a, T Zhao, H Wang, H Tian, O Xu, X Zhu… - Materials Today Bio, 2023 - Elsevier
Mitochondrial dysfunction causes the production of reactive oxygen species (ROS) and
oxidative damage, and oxidative stress and inflammation are considered key factors causing …

Recent progress of micro/nanorobots for cell delivery and manipulation

W Chen, H Zhou, B Zhang, Q Cao… - Advanced Functional …, 2022 - Wiley Online Library
Micro/nanorobots have attracted significant interest in the biomedical field due to their
micro/nano scale sizes and autonomously untethered motions. Meanwhile, stem cell‐based …

Graphene‐based biomaterials for bone regenerative engineering: a comprehensive review of the field and considerations regarding biocompatibility and …

L Daneshmandi, M Barajaa… - Advanced …, 2021 - Wiley Online Library
Graphene and its derivatives have continued to garner worldwide interest due to their
unique characteristics. Having expanded into biomedical applications, there have been …

Wharton's jelly mesenchymal stem cells: a concise review of their secretome and prospective clinical applications

H Drobiova, S Sindhu, R Ahmad, D Haddad… - Frontiers in Cell and …, 2023 - frontiersin.org
Accumulating evidence indicates that most primary Wharton's jelly mesenchymal stem cells
(WJ-MSCs) therapeutic potential is due to their paracrine activity, ie, their ability to modulate …

Bioengineering extracellular vesicles: smart nanomaterials for bone regeneration

K Man, NM Eisenstein, DA Hoey, SC Cox - Journal of Nanobiotechnology, 2023 - Springer
In the past decade, extracellular vesicles (EVs) have emerged as key regulators of bone
development, homeostasis and repair. EV-based therapies have the potential to …

Targeting the central nervous system: From synthetic nanoparticles to extracellular vesicles—Focus on Alzheimer's and Parkinson's disease

S Hernando, E Santos‐Vizcaíno… - Wiley …, 2023 - Wiley Online Library
Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD) and Parkinson's
disease (PD) are an accelerating global health problem as life expectancy rises worldwide …