A mechanistic review of β-carotene, lutein, and zeaxanthin in eye health and disease

FT Johra, AK Bepari, AT Bristy, HM Reza - Antioxidants, 2020 - mdpi.com
Carotenoids are natural lipid-soluble antioxidants abundantly found as colorful pigments in
fruits and vegetables. At least 600 carotenoids occur naturally, although about 20 of them …

Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications

MA Mengstie, E Chekol Abebe… - Frontiers in molecular …, 2022 - frontiersin.org
Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to
long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels. By …

A review on mechanism of inhibition of advanced glycation end products formation by plant derived polyphenolic compounds

S Anwar, S Khan, A Almatroudi, AA Khan… - Molecular Biology …, 2021 - Springer
Advanced glycation end products (AGEs) are naturally occurring biomolecules formed by
interaction of reducing sugars with biomolecules such as protein and lipids etc., Long term …

C-glucosidic ellagitannins and galloylated glucoses as potential functional food ingredients with anti-diabetic properties: A study of α-glucosidase and α-amylase …

N Cardullo, V Muccilli, L Pulvirenti, A Cornu… - Food chemistry, 2020 - Elsevier
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia, which can be
counteracted by inhibition of α-glucosidase and α-amylase, both involved in the …

Neuroinflammation in Alzheimer's disease: the preventive and therapeutic potential of polyphenolic nutraceuticals

Y Sawikr, NS Yarla, I Peluso, MA Kamal, G Aliev… - Advances in protein …, 2017 - Elsevier
Brain inflammation, characterized by increased microglia and astrocyte activation, increases
during aging and is a key feature of neurodegenerative diseases, such as Alzheimer's …

Research advances on the damage mechanism of skin glycation and related inhibitors

W Zheng, H Li, Y Go, XH Chan, Q Huang, J Wu - Nutrients, 2022 - mdpi.com
Our skin is an organ with the largest contact area between the human body and the external
environment. Skin aging is affected directly by both endogenous factors and exogenous …

A review on prevention of glycation of proteins: Potential therapeutic substances to mitigate the severity of diabetes complications

S Sarmah, AS Roy - International Journal of Biological Macromolecules, 2022 - Elsevier
Non-enzymatic reaction involving carbonyl of reducing sugars and amino groups in proteins
produces advanced glycation end products (AGEs). AGE accumulation in vivo is a crucial …

Polyphenols and AGEs/RAGE axis. Trends and challenges

I González, MA Morales, A Rojas - Food Research International, 2020 - Elsevier
The formation of advanced glycation end-products (AGEs) is a key pathophysiological event
linked not only to the onset and progression of diabetic complications, but also to …

AGEs accumulation with vascular complications, glycemic control and metabolic syndrome: A narrative review

R Pal, SK Bhadada - Bone, 2023 - Elsevier
Background Multiple pathogenetic mechanisms are involved in the genesis of various
microvascular and macrovascular complications of diabetes mellitus. Of all these, advanced …

Advanced glycation end products in the skin: Molecular mechanisms, methods of measurement, and inhibitory pathways

C Chen, JQ Zhang, L Li, M Guo, Y He, Y Dong… - Frontiers in …, 2022 - frontiersin.org
Advanced glycation end products (AGEs) are a series of stable compounds produced under
non-enzymatic conditions by the amino groups of biomacromolecules and the free carbonyl …