Current best practices in single‐cell RNA‐seq analysis: a tutorial
Single‐cell RNA‐seq has enabled gene expression to be studied at an unprecedented
resolution. The promise of this technology is attracting a growing user base for single‐cell …
resolution. The promise of this technology is attracting a growing user base for single‐cell …
The Perseus computational platform for comprehensive analysis of (prote) omics data
A main bottleneck in proteomics is the downstream biological analysis of highly multivariate
quantitative protein abundance data generated using mass-spectrometry-based analysis …
quantitative protein abundance data generated using mass-spectrometry-based analysis …
Welcome to the Tidyverse
At a high level, the tidyverse is a language for solving data science challenges with R code.
Its primary goal is to facilitate a conversation between a human and a computer about data …
Its primary goal is to facilitate a conversation between a human and a computer about data …
ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R
After more than fifteen years of existence, the R package ape has continuously grown its
contents, and has been used by a growing community of users. The release of version 5.0 …
contents, and has been used by a growing community of users. The release of version 5.0 …
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
To the Editor—Rapid advances in DNA-sequencing and bioinformatics technologies in the
past two decades have substantially improved understanding of the microbial world. This …
past two decades have substantially improved understanding of the microbial world. This …
SCANPY: large-scale single-cell gene expression data analysis
Scanpy is a scalable toolkit for analyzing single-cell gene expression data. It includes
methods for preprocessing, visualization, clustering, pseudotime and trajectory inference …
methods for preprocessing, visualization, clustering, pseudotime and trajectory inference …
[HTML][HTML] The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads
Abstract We present Rsubread, a Bioconductor software package that provides high-
performance alignment and read counting functions for RNA-seq reads. Rsubread is based …
performance alignment and read counting functions for RNA-seq reads. Rsubread is based …
Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown
High-throughput sequencing of mRNA (RNA-seq) has become the standard method for
measuring and comparing the levels of gene expression in a wide variety of species and …
measuring and comparing the levels of gene expression in a wide variety of species and …
[HTML][HTML] Spatial transcriptomics and in situ sequencing to study Alzheimer's disease
Although complex inflammatory-like alterations are observed around the amyloid plaques of
Alzheimer's disease (AD), little is known about the molecular changes and cellular …
Alzheimer's disease (AD), little is known about the molecular changes and cellular …
TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data
Abstract The Cancer Genome Atlas (TCGA) research network has made public a large
collection of clinical and molecular phenotypes of more than 10 000 tumor patients across …
collection of clinical and molecular phenotypes of more than 10 000 tumor patients across …