This perspective considers ways in which the field of microfluidics can increase its impact by
improving existing technologies and enabling new functionalities. We highlight applications …

Abstract The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is
becoming an essential tool in cancer research as it expresses an intermediate complexity …

Predicting the effects of drugs before human clinical trials is at the heart of drug screening
and discovery processes. The cost of drug discovery is steadily increasing owing to the …

Lab-on-a-chip devices leverage microfluidic technologies to enable chemical and biological
processes at small scales. However, existing microfluidic channel networks are typically …

Droplet microfluidic technology provides a new platform for controllable generation of
microdroplets and droplet-derived materials. In particular, because of the ability in high …

We present a programmable droplet-based microfluidic device that combines the
reconfigurable flow-routing capabilities of integrated microvalve technology with the sample …

Novel applications of micro total analysis systems (μTAS) are addressing fundamental
biological questions, creating new biomedical reagents, and develo** innovative cell and …

Methods for single-cell analysis are critical to revealing cell-to-cell variability in biological
systems, especially in cases where relevant minority cell populations can be obscured by …

Assay devices designed for these applications offer improvements to existing methods or
provide fundamentally new strategies. Both mature methods and novel techniques have …

We review recent progress in miniaturized dielectric elastomer actuators (DEAs), sensors,
and energy harvesters. We focus primarily on configurations where the large strain, high …