Wound healing is a complex process that consists of multiple phases, each of which are
indispensable for adequate repair. Timely initiation and resolution of each of these phases …

Urokinase-type plasminogen activator receptor (uPAR) expression is elevated during
inflammation and tissue remodelling and in many human cancers, in which it frequently …

This is the second of 2 articles that discuss the biology and pathophysiology of wound
healing, reviewing the role that growth factors play in this process and describing the current …

Plasma membrane urokinase-type plasminogen activator (uPA)-receptor (uPAR) is a GPI-
anchored protein that binds with high-affinity and activates the serine protease uPA, thus …

Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-
inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease …

The process of repair of wounded skin involves intricate orchestration not only between the
epidermal and dermal compartments but also between the resident and immigrant cells and …

Summary The RAS-stimulated RAF-MEK-ERK pathway confers epithelial cells with critical
motile and invasive capacities during development, tissue regeneration, and carcinoma …

Currently, there are several studies supporting the role of urokinase‐type plasminogen
activator (uPA) system in cancer. The association of uPA to its receptor triggers the …

Our understanding of the regulatory processes of reepithelialization during wound healing is
incomplete. In an attempt to map the genes involved in epidermal regeneration and …

Proteolysis is a key event in several biological processes; proteolysis must be tightly
controlled because its improper activation leads to dramatic consequences. Deregulation of …