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SARS-CoV-2 variant biology: immune escape, transmission and fitness
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …
challenge in this century. Two years after its emergence, the rapid development and …
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants
Abstract In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified,
and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that …
and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that …
Emergence of SARS-CoV-2 omicron lineages BA. 4 and BA. 5 in South Africa
Abstract Three lineages (BA. 1, BA. 2 and BA. 3) of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …
coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant
The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern. In
this study, our statistical modelling suggests that Omicron has spread more rapidly than the …
this study, our statistical modelling suggests that Omicron has spread more rapidly than the …
Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation
During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations
have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 …
have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 …
[HTML][HTML] Virological characteristics of the SARS-CoV-2 Omicron BA. 2 spike
Soon after the emergence and global spread of the SARS-CoV-2 Omicron lineage BA. 1,
another Omicron lineage, BA. 2, began outcompeting BA. 1. The results of statistical analysis …
another Omicron lineage, BA. 2, began outcompeting BA. 1. The results of statistical analysis …
Virological characteristics of the SARS-CoV-2 Omicron BA. 2 subvariants, including BA. 4 and BA. 5
After the global spread of the SARS-CoV-2 Omicron BA. 2, some BA. 2 subvariants,
including BA. 2.9. 1, BA. 2.11, BA. 2.12. 1, BA. 4, and BA. 5, emerged in multiple countries …
including BA. 2.9. 1, BA. 2.11, BA. 2.12. 1, BA. 4, and BA. 5, emerged in multiple countries …
The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …