Aqueous microdroplets enable abiotic synthesis and chain extension of unique peptide isomers from free amino acids
Amide bond formation, the essential condensation reaction underlying peptide synthesis, is
hindered in aqueous systems by the thermodynamic constraints associated with …
hindered in aqueous systems by the thermodynamic constraints associated with …
Emerging microdroplet chemistry for synthesis and analysis
X Yan - International Journal of Mass Spectrometry, 2021 - Elsevier
Recent studies have shown that remarkable reaction acceleration can be achieved at the
air/solution interface of microdroplets. The unique environment of microdroplets can drive …
air/solution interface of microdroplets. The unique environment of microdroplets can drive …
Chemical kinetics in microdroplets
Micrometer-sized compartments play significant roles in driving heterogeneous
transformations within atmospheric and biochemical systems as well as providing vehicles …
transformations within atmospheric and biochemical systems as well as providing vehicles …
Electrostatics and chemical reactivity at the air–water interface
MTC Martins-Costa, MF Ruiz-López - Journal of the American …, 2023 - ACS Publications
It has been recently discovered that chemical reactions at aqueous interfaces can be orders
of magnitude faster compared to conventional bulk phase reactions, but despite its wide …
of magnitude faster compared to conventional bulk phase reactions, but despite its wide …
Accelerated reactions of amines with carbon dioxide driven by superacid at the microdroplet interface
Microdroplets display distinctive interfacial chemistry, manifested as accelerated reactions
relative to those observed for the same reagents in bulk. Carbon dioxide undergoes C–N …
relative to those observed for the same reagents in bulk. Carbon dioxide undergoes C–N …
A critical analysis of electrospray techniques for the determination of accelerated rates and mechanisms of chemical reactions in droplets
Electrospray and Electrosonic Spray Ionization Mass Spectrometry (ESI-MS and ESSI-MS)
have been widely used to report evidence that many chemical reactions in micro-and nano …
have been widely used to report evidence that many chemical reactions in micro-and nano …
Water Charge Transfer Accelerates Criegee Intermediate Reaction with H2O– Radical Anion at the Aqueous Interface
Criegee intermediates (CIs) are important carbonyl oxides that may react with atmospheric
trace chemicals and impact the global climate. The CI reaction with water has been widely …
trace chemicals and impact the global climate. The CI reaction with water has been widely …
Aqueous microdroplets promote C–C bond formation and sequences in the reverse tricarboxylic acid cycle
Y Ju, H Zhang, Y Jiang, W Wang, G Kan, K Yu… - Nature Ecology & …, 2023 - nature.com
The reverse tricarboxylic acid cycle (rTCA) is a central anabolic network that uses carbon
dioxide (CO2) and may have provided complex carbon substrates for life before the advent …
dioxide (CO2) and may have provided complex carbon substrates for life before the advent …
A kinetic description of how interfaces accelerate reactions in micro-compartments
A kinetic expression is derived to explain how interfaces alter bulk chemical equilibria and
accelerate reactions in micro-compartments. This description, aided by the development of a …
accelerate reactions in micro-compartments. This description, aided by the development of a …
Accelerated microdroplet synthesis of benzimidazoles by nucleophilic addition to protonated carboxylic acids
We report a metal-free novel route for the accelerated synthesis of benzimidazole and its
derivatives in the ambient atmosphere. The synthetic procedure involves 1, 2-aromatic …
derivatives in the ambient atmosphere. The synthetic procedure involves 1, 2-aromatic …