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The biology and function of extracellular vesicles in immune response and immunity
Extracellular vesicles (EVs), such as ectosomes and exosomes, contain DNA, RNA, proteins
and are encased in a phospholipid bilayer. EVs provide intralumenal cargo for delivery into …
and are encased in a phospholipid bilayer. EVs provide intralumenal cargo for delivery into …
A beginner's guide to study extracellular vesicles in human blood plasma and serum
Blood is the most commonly used body fluid for obtaining and studying extracellular vesicles
(EVs). While blood is a standard choice for clinical analysis, using blood as a source of EVs …
(EVs). While blood is a standard choice for clinical analysis, using blood as a source of EVs …
A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secretion
Exosomes are secreted to the extracellular milieu when multivesicular endosomes (MVEs)
dock and fuse with the plasma membrane. However, MVEs are also known to fuse with …
dock and fuse with the plasma membrane. However, MVEs are also known to fuse with …
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis
Intracellular surveillance for systemic microbial components during homeostasis and
infections governs host physiology and immunity. However, a long-standing question is how …
infections governs host physiology and immunity. However, a long-standing question is how …
[HTML][HTML] High throughput and rapid isolation of extracellular vesicles and exosomes with purity using size exclusion liquid chromatography
Extracellular vesicles (EVs) have emerged as potential biomarkers for diagnosing a range of
diseases without invasive procedures. Extracellular vesicles also offer advantages …
diseases without invasive procedures. Extracellular vesicles also offer advantages …
Therapeutic potential in rheumatic diseases of extracellular vesicles derived from mesenchymal stromal cells
The incidence of rheumatic diseases such as rheumatoid arthritis and osteoarthritis and
injuries to articular cartilage that lead to osteochondral defects is predicted to rise as a result …
injuries to articular cartilage that lead to osteochondral defects is predicted to rise as a result …
Diversity in connexin biology
Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …
employed to assemble semicrystalline clusters of intercellular channels that had been well …
Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases
J Zhu, S Wang, D Yang, W Xu, H Qian - Journal of Nanobiotechnology, 2023 - Springer
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
[HTML][HTML] Extracellular vesicles meet mitochondria: Potential roles in regenerative medicine
S Wu, T Yang, M Ma, L Fan, L Ren, G Liu… - Pharmacological …, 2024 - Elsevier
Extracellular vesicles (EVs), secreted by most cells, act as natural cell-derived carriers for
delivering proteins, nucleic acids, and organelles between cells. Mitochondria are highly …
delivering proteins, nucleic acids, and organelles between cells. Mitochondria are highly …
[HTML][HTML] Potential applications of using tissue-specific EVs in targeted therapy and vaccinology
TP Lehmann, M Golik, J Olejnik, M Łukaszewska… - Biomedicine & …, 2023 - Elsevier
Many cell types secrete spherical membrane bodies classified as extracellular vesicles
(EVs). EVs participate in intercellular communication and are present in body fluids …
(EVs). EVs participate in intercellular communication and are present in body fluids …