[HTML][HTML] Anatomical, physiological, and functional diversity of adipose tissue

RK Zwick, CF Guerrero-Juarez, V Horsley, MV Plikus - Cell metabolism, 2018‏ - cell.com
Adipose tissue depots can exist in close association with other organs, where they assume
diverse, often non-traditional functions. In stem cell-rich skin, bone marrow, and mammary …

WNT5B in Physiology and Disease

S Suthon, RS Perkins, V Bryja… - Frontiers in cell and …, 2021‏ - frontiersin.org
WNT5B, a member of the WNT family of proteins that is closely related to WNT5A, is required
for cell migration, cell proliferation, or cell differentiation in many cell types. WNT5B signals …

Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway

Z Liang, L Liu, R Gao, C Che, G Yang - Cellular & Molecular Biology …, 2022‏ - Springer
Background Current studies show that exosomal miRNAs become an important factor in
cancer metastasis. Among the many miRNA studies, miR-7-5p has not been thoroughly …

Prioritizing network communities

M Zitnik, R Sosič, J Leskovec - Nature communications, 2018‏ - nature.com
Uncovering modular structure in networks is fundamental for systems in biology, physics,
and engineering. Community detection identifies candidate modules as hypotheses, which …

Organoid models for mammary gland dynamics and breast cancer

V Srivastava, TR Huycke, KT Phong… - Current opinion in cell …, 2020‏ - Elsevier
The mammary gland is a highly dynamic tissue that undergoes repeated cycles of growth
and involution during pregnancy and menstruation. It is also the site from which breast …

The role of wnt signaling in diabetes-induced osteoporosis

K Bao, Y Jiao, L **ng, F Zhang, F Tian - Diabetology & Metabolic …, 2023‏ - Springer
Osteoporosis, a chronic complication of diabetes mellitus, is characterized by a reduction in
bone mass, destruction of bone microarchitecture, decreased bone strength, and increased …

Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis

Y Luan, J Hu, Q Wang, X Wang, W Li, R Qu, C Yang… - Cell reports, 2024‏ - cell.com
Neutrophils are important innate immune cells with plasticity, heterogenicity, and functional
ambivalency. While bone marrow is often regarded as the primary source of neutrophil …

Secretome of Cancer-Associated Fibroblasts (CAFs) Influences Drug Sensitivity in Cancer Cells

R Lau, L Yu, TI Roumeliotis, A Stewart… - Journal of Proteome …, 2024‏ - ACS Publications
Resistance is a major problem with effective cancer treatment and the stroma forms a
significant portion of the tumor mass but traditional drug screens involve cancer cells alone …

WNT5A as a therapeutic target in breast cancer

CP Prasad, M Manchanda, P Mohapatra… - Cancer and Metastasis …, 2018‏ - Springer
Despite the clinical development of novel adjuvant and neoadjuvant chemotherapeutic
drugs, metastatic breast cancer is one of the leading causes of cancer-related death among …

The molecular mechanisms of remodeling in asthma, COPD and IPF with a special emphasis on the complex role of Wnt5A

A Singla, S Reuter, C Taube, M Peters, K Peters - Inflammation Research, 2023‏ - Springer
Introduction Chronic inflammatory lung diseases are a common cause of suffering and
death. Chronic obstructive pulmonary disease (COPD) is the reason for 6% of all deaths …