Chronic low-grade inflammation and neuronal deregulation are two components of a
smoldering disease activity that drives the progression of disability in people with multiple …

Reelin was originally identified as a regulator of neuronal migration and synaptic function,
but its non-neuronal functions have received far less attention. Reelin participates in organ …

The low-density lipoprotein receptor (LDLR) gene family includes LDLR, very LDLR, and
LDL receptor–related proteins (LRPs) such as LRP1, LRP1b (aka LRP-DIT), LRP2 (aka …

Thromboembolic complications and excessive inflammation are frequent in severe COVID-
19, potentially leading to long COVID. In non-COVID studies, we and others demonstrated …

This review article summarizes 20 years of our research on hepatic stellate cells within the
framework of two collaborative research centers CRC575 and CRC974 at the Heinrich …

Reelin, an extracellular matrix protein with putative antidepressant-like properties, becomes
dysregulated by chronic stress. Improvement in cognitive dysfunction and depression-like …

Objective: Reelin and its receptor Apoer2 (apolipoprotein E receptor 2) play a prominent role
in endothelial cell dysfunction by promoting leukocyte–endothelial cell adhesion, an …

Reelin, a large extracellular glycoprotein, plays critical roles in neuronal development and
synaptic plasticity in the central nervous system (CNS). Recent studies have revealed non …

The purpose of this study was to evaluate the effects of Dab1 gene silencing on the
immunoexpression of light chain 3 beta (Lc3b), glucose regulating protein 78 (Grp78), heat …

In the pathogenesis of autoimmune disorders, the modulation of leukocytes′ trafficking
plays a central role, still poorly understood. Here, we focused on the effect of TLR2 ligands …