All-atom molecular dynamics simulations have become increasingly popular as a tool to
investigate protein function and dynamics. However, researchers are concerned about the …

How metazoan mechanotransduction channels sense mechanical stimuli is not well
understood. The NOMPC channel in the transient receptor potential (TRP) family, a …

The cellular and molecular basis of vertebrate touch reception remains least understood
among the traditional five senses. Somatosensory afferents that innervate the skin encode …

The Drosophila auditory organ shares equivalent transduction mechanisms with vertebrate
hair cells, and both are specified by atonal family genes. Using a whole-organ knockout …

Mosquitoes, certain Drosophila species, and honey bees use Johnston's organ in their
antennae to detect the wing-beat sounds of conspecifics. Recent studies on these insects …

Development of a functional auditory system in Drosophila requires specification and
differentiation of the chordotonal sensilla of Johnston's organ (JO) in the antenna, correct …

Johnston's organ–the hearing organ of Drosophila–has a very different structure and
morphology to that of the hearing organs of vertebrates. Nevertheless, it is becoming clear …

Acoustic communication in flies is based on the production and perception of courtship
song. Drosophila males sing to females during the courtship ritual, while females listen for …

Mechanosensory transduction underlies the perception of touch, sound and acceleration.
The mechanical signals exist in the environment are resensed by the specialized …

Nociception is a protective mechanism that mediates behavioral responses to a range of
potentially damaging stimuli, including noxious temperature, chemicals, and mechanical …