Risk and protective factors for COVID-19 morbidity, severity, and mortality

J Zhang, X Dong, G Liu, Y Gao - Clinical reviews in allergy & immunology, 2023 - Springer
The outbreak of the coronavirus disease 2019 (COVID-19), caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become an evolving global …

Infectious Diseases Society of America guidelines on the treatment and management of patients with COVID-19 (September 2022)

A Bhimraj, RL Morgan, AH Shumaker… - Clinical Infectious …, 2024 - academic.oup.com
There are many pharmacologic therapies that are being used or considered for treatment of
coronavirus disease 2019 (COVID-19), with rapidly changing efficacy and safety evidence …

Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

Sex and gender in asthma

NU Chowdhury, VP Guntur… - European …, 2021 - publications.ersnet.org
Asthma is a heterogenous disease, and its prevalence and severity are different in males
versus females through various ages. As children, boys have an increased prevalence of …

Infectious Diseases Society of America Guidelines on the treatment and management of patients with COVID-19 (April 2020)

A Bhimraj, RL Morgan, AH Shumaker… - Clinical Infectious …, 2024 - academic.oup.com
Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …

ACE2: the major cell entry receptor for SARS-CoV-2

F Scialo, A Daniele, F Amato, L Pastore, MG Matera… - Lung, 2020 - Springer
Despite the unprecedented effort of the scientific community, the novel SARS-CoV-2 virus
has infected more than 46 million people worldwide, killing over one million two hundred …

[HTML][HTML] Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

S Ramakrishnan, DV Nicolau, B Langford… - The Lancet …, 2021 - thelancet.com
Background Multiple early reports of patients admitted to hospital with COVID-19 showed
that patients with chronic respiratory disease were significantly under-represented in these …

[HTML][HTML] Covid-19 and COPD

JM Leung, M Niikura, CWT Yang… - European Respiratory …, 2020 - publications.ersnet.org
As of 11 July, 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
virus responsible for the coronavirus disease 2019 (COVID-19) pandemic has infected over …

Recent developments in the immunopathology of COVID‐19

H Zhang, Y Sun, Y Wang, D Yazici, D Azkur, I Ogulur… - Allergy, 2023 - Wiley Online Library
There has been an important change in the clinical characteristics and immune profile of
Coronavirus disease 2019 (COVID‐19) patients during the pandemic thanks to the …

Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive …

LM Yu, M Bafadhel, J Dorward, G Hayward, BR Saville… - The Lancet, 2021 - thelancet.com
Background A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in
patients not admitted to hospital, but effectiveness in high-risk individuals is unknown. We …