[HTML][HTML] In silico molecular docking and ADME/T analysis of Quercetin compound with its evaluation of broad-spectrum therapeutic potential against particular …

MM Hasan, Z Khan, MS Chowdhury, MA Khan… - Informatics in Medicine …, 2022 - Elsevier
Progression in computational research has made it possible for the in silico methods to offer
epochal benefits to both regulatory needs and the pharmaceutical industry to assess the …

Network pharmacology-based analysis for unraveling potential cancer-related molecular targets of Egyptian propolis phytoconstituents accompanied with molecular …

RS Ibrahim, AA El-Banna - RSC advances, 2021 - pubs.rsc.org
Cancer is one of the predominant causes of death worldwide. The new trend nowadays is to
exploit natural products with the hope of develo** new anticancer agents with fewer side …

Phytoconstituents of traditional Himalayan Herbs as potential inhibitors of Human Papillomavirus (HPV-18) for cervical cancer treatment: An In silico Approach

D Salaria, R Rolta, J Mehta, O Awofisayo, OA Fadare… - PLoS …, 2022 - journals.plos.org
Human papillomavirus (HPV) induced cervical cancer is becoming a major cause of
mortality in women. The present research aimed to identify the natural inhibitors of HPV-18 …

[PDF][PDF] Design and molecular docking studies of novel antimicrobial peptides using autodock molecular docking software

K Kaur, P Kaur, A Mittal, SK Nayak… - Asian Journal of …, 2017 - researchgate.net
Objective: Design of novel antimicrobial peptides (AMPs) and study through the molecular
docking. Methods: The molecular structures were drawn in ChemBiodraw ultra and by the …

[PDF][PDF] Phytochemical profiling of mangosteen fruit, Garcinia mangostana

I Manimekalai, K Sivakumari, K Ashok… - World J Pharm Pharm …, 2016 - researchgate.net
The present study deals with phytochemical profiling of epicarp and endocarp extracts of
mangosteen fruit, Garcinia mangostana. Fresh fruits were procured from market, identified …

In silico docking to explicate interface between plant-originated inhibitors and E6 oncogenic protein of highly threatening human papillomavirus 18

S Kumar, L Jena, M Sahoo, M Kakde… - Genomics & …, 2015 - pmc.ncbi.nlm.nih.gov
The leading cause of cancer mortality globally amongst the women is due to human
papillomavirus (HPV) infection. There is need to explore anti-cancerous drugs against this …

In silico molecular docking studies of quercetin compound against anti-inflammatory and anticancer proteins

P Parameswari, R Devika - Research Journal of Pharmacy and …, 2019 - indianjournals.com
Quercetin (a plant flavonoid) having a spot with polyphenol extensively disseminated in
nature. Quercetin has aglycone structure and other flavonoid glycosides are rutin and …

Novel ferrocenylbisphosphonate hybrid compounds: Synthesis, characterization and potent activity against cancer cell lines

CG Anusionwu, BA Aderibigbe, SA Adeyemi… - Bioorganic & Medicinal …, 2022 - Elsevier
The toxicity of existing anticancer agents on healthy cells and the emergence of multidrug-
resistance cancer cells have led to the search for less toxic anticancer agents with different …

Thiocolchicoside and colchicine induced apoptosis in breast cancer (MCF-7) cells via up-regulated expression of p53 tumor suppressor protein gene: an in vitro and …

D Mahendran, K Selvam, S Kumari… - Journal of Biologically …, 2020 - Taylor & Francis
This study describes the antiproliferative activity of thiocolchicoside and colchicine
compounds in a dose-dependent manner against breast cancer cell line (MCF-7). MTT …

A network-biology led computational drug repurposing strategy to prioritize therapeutic options for COVID-19

P Khurana, R Varshney, A Gupta - Heliyon, 2022 - cell.com
The alarming pandemic situation of novel Severe Acute Respiratory Syndrome Coronavirus
2 (nSARS-CoV-2) infection, high drug development cost and slow process of drug discovery …