Brugada syndrome (BrS) is diagnosed by a coved-type ST-segment elevation in the right
precordial leads on the electrocardiogram (ECG), and it is associated with an increased risk …

Bone regeneration using bioactive molecules and biocompatible materials is growing
steadily with the advent of the new findings in cellular signaling. Bone Morphogenetic …

Complex interplay between cardiac tissues is crucial for their integrity. The flow responsive
transcription factor KLF2, which is expressed in the endocardium, is vital for cardiovascular …

Arrhythmias in Brugada syndrome patients originate in the right ventricular outflow tract
(RVOT). Over the past few decades, the characterization of the unique anatomy and …

Trabecular morphogenesis is a key morphologic event during cardiogenesis and contributes
to the formation of a competent ventricular wall. Lack of trabeculation results in embryonic …

Heart failure is a global health burden responsible for high morbidity and mortality with a
prevalence of greater than 60 million individuals worldwide. One of the major causes of …

Although papillary thyroid carcinoma (PTC) has a favorable prognosis after surgical or
medical treatment, its survival rate is still very low. Therefore, finding more reliable therapy …

The design of cell-instructive biomaterials for tissue engineering and regenerative medicine
is at a crossroads. Although the conventional tissue engineering approach is top-down (cells …

Energy deprivation and metabolic rewiring of cardiomyocytes are widely recognized
hallmarks of heart failure. Here, we report that HEY2 (a Hairy/Enhancer-of-split-related …

Hypoplastic left heart syndrome (HLHS) is a lethal congenital heart disease (CHD) affecting
8–25 per 100,000 neonates globally. Clinical interventions, primarily surgical, have …