Nanomaterials as assisted matrix of laser desorption/ionization time-of-flight mass spectrometry for the analysis of small molecules

M Lu, X Yang, Y Yang, P Qin, X Wu, Z Cai - Nanomaterials, 2017 - mdpi.com
Matrix-assisted laser desorption/ionization (MALDI), a soft ionization method, coupling with
time-of-flight mass spectrometry (TOF MS) has become an indispensible tool for analyzing …

MALDI matrices for the analysis of low molecular weight compounds: rational design, challenges and perspectives

Z Qiao, F Lissel - Chemistry–An Asian Journal, 2021 - Wiley Online Library
The analysis of low molecular weight (LMW) compounds is of great interest to detect small
pharmaceutical drugs rapidly and sensitively, or to trace and understand metabolic …

Matrix-assisted laser desorption/ionization mass spectrometry: mechanistic studies and methods for improving the structural identification of carbohydrates

YH Lai, YS Wang - Mass Spectrometry, 2017 - jstage.jst.go.jp
Although matrix-assisted laser desorption/ionization (MALDI) mass spectrometry is one of
the most widely used soft ionization methods for biomolecules, the lack of detailed …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: an update for 2015–2016

DJ Harvey - Mass Spectrometry Reviews, 2021 - Wiley Online Library
This review is the ninth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Glycoproteomic alterations in drug-resistant nonsmall cell lung cancer cells revealed by lectin magnetic nanoprobe-based mass spectrometry

JT Waniwan, YJ Chen, R Capangpangan… - Journal of proteome …, 2018 - ACS Publications
Understanding the functional role of glycosylation-mediated pathogenesis requires deep
characterization of glycoproteome, which remains extremely challenging due to the …

Mass spectrometry for protein sialoglycosylation

Q Zhang, Z Li, Y Wang, Q Zheng… - Mass Spectrometry …, 2018 - Wiley Online Library
Sialic acids are a family of structurally unique and negatively charged nine‐carbon sugars,
normally found at the terminal positions of glycan chains on glycoproteins and glycolipids …

Direct oligosaccharide profiling using thin-layer chromatography coupled with ionic liquid-stabilized nanomatrix-assisted laser desorption-ionization mass …

EG Mernie, LD Tolesa, MJ Lee, MC Tseng… - Analytical …, 2019 - ACS Publications
The in-depth characterization of glycan structures is crucial to understanding their structure–
function relationships and their effects on health and various diseases. Despite advances in …

Structural identification of carbohydrate isomers using ambient infrared-assisted dissociation

YH Lai, W Leung, PH Chang, WX Zhou, YS Wang - Analytica Chimica Acta, 2023 - Elsevier
Informative dissociation of carbohydrates using an infrared (IR) irradiation system is
demonstrated under ambient conditions without the instrumentation of a mass spectrometer …

Surface effects of iron oxide nanoparticles on the MALDI in-source decay analysis of glycans and peptides

AJ Antone, Q Liang, JA Sherwood… - ACS Applied Nano …, 2019 - ACS Publications
Inorganic nanoparticles as MALDI matrices have recently been explored to study the
molecular mass determination and structural analysis of glycans and peptides. However, the …

Rapid detection of perfluorinated sulfonic acids through preconcentration by bubble bursting and surface‐assisted laser desorption/ionization

C Lee, TL Yang, YZ Yao, JY Li… - Journal of Mass …, 2021 - Wiley Online Library
We developed a preconcentration method in which aerosol droplets containing enriched
perfluorinated sulfonic acids (PFSs) are generated through bubble bursting and collected …