Therapeutic potential of pyrrole and pyrrolidine analogs: an update
N Jeelan Basha, SM Basavarajaiah, K Shyamsunder - Molecular Diversity, 2022 - Springer
The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has
been a versatile field of study for a long time for its diverse biological and medicinal …
been a versatile field of study for a long time for its diverse biological and medicinal …
Recent Advances on α‐Azidoketones and Esters in the Synthesis of N‐Heterocycles
L Borkotoky, RA Maurya - Asian Journal of Organic Chemistry, 2022 - Wiley Online Library
Organic azides have been proven to possess versatile reactivity that is utilized to synthesize
a large number of molecular scaffolds. Among the azides, α‐azidoketones and esters have …
a large number of molecular scaffolds. Among the azides, α‐azidoketones and esters have …
Regioselective Access to 1,2,4-Triazole-Fused N-Heterocycle, Pyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine, via Double Dehydrative Cyclizations
H Oh, H Kim, I Kim - The Journal of Organic Chemistry, 2023 - ACS Publications
A highly efficient and regioselective approach to a novel 1, 2, 4-triazole-fused N-heterocyclic
scaffold, pyrrolo [1, 2-a][1, 2, 4] triazolo [3, 4-c] pyrazine, was established by base-promoted …
scaffold, pyrrolo [1, 2-a][1, 2, 4] triazolo [3, 4-c] pyrazine, was established by base-promoted …
Recent advances in the synthesis of N-fused heterocycles from N-aroylmethylpyrrole-2-carboxaldehyde derivatives via annulative functionalization strategies
DR Joshi, I Kim - Tetrahedron, 2024 - Elsevier
Due to growing interest in nitrogen-fused heterocycles with versatile usages, tremendous
progress has been made on synthetic strategies to enable access to these compounds for …
progress has been made on synthetic strategies to enable access to these compounds for …
One-Pot Four-Component Coupling Approach to Polyheterocycles: 6H-Furo[3,2-f]pyrrolo[1,2-d][1,4]diazepine
SH Yoon, SJ Kim, I Kim - The Journal of Organic Chemistry, 2020 - ACS Publications
A novel polyheterocyclic chemical space, 6 H-furo [3, 2-f] pyrrolo [1, 2-d][1, 4] diazepine, was
generated by a one-pot four-component coupling reaction where multiple bonds (three C–C …
generated by a one-pot four-component coupling reaction where multiple bonds (three C–C …
Sodium Azide: An Inorganic Nitrogen Source for the Synthesis of Organic N‐Compounds
Z Tashrifi, MM Khanaposhtani, B Larijani… - …, 2021 - Wiley Online Library
Sodium azide (NaN3) is a colorless or white crystalline salt with diverse medicinal and
industrial applications. Recently, NaN3 is considered as an inexpensive and valuable …
industrial applications. Recently, NaN3 is considered as an inexpensive and valuable …
Pyrrolopyrazine derivatives: synthetic approaches and biological activities
Nitrogen-containing heterocycles were employed in different applications such as
pharmaceuticals, organic materials, natural products, and mainly in bioactive molecules …
pharmaceuticals, organic materials, natural products, and mainly in bioactive molecules …
Decade Advances of NaN3 in Three‐component Reactions
ZY Wang, J Li, N Wang, H Liu… - Asian Journal of Organic …, 2023 - Wiley Online Library
Decade advances of sodium azide (2011–2022) have been summarized via mechanisms
and target products. Sodium azide is commonly used as a nucleophile (N3−) or radical …
and target products. Sodium azide is commonly used as a nucleophile (N3−) or radical …
A regioselective [4+ 2] annulation approach to 5-acylindolizine-7-carbonitriles: generation of poly-substituted pyridines
S Kim, JH Lee, SH Yoon, I Kim - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
The reaction of β-ketonitrile and N-substituted pyrrole-2-carboxaldehyde in the presence of
piperidinium acetate in CH3CN permitted regioselective access to 5-acylindolizine-7 …
piperidinium acetate in CH3CN permitted regioselective access to 5-acylindolizine-7 …
Expansion of diazepine heterocyclic chemical space via sequential Knoevenagel condensation-intramolecular aza-Wittig reaction: 2-acyl-4-aryl-5 H-pyrrolo [1, 2-d][1 …
A Dagar, I Kim - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
A highly efficient synthetic route to a new 1, 4-diazepene skeleton, 2-acyl-4-aryl-5H-pyrrolo
[1, 2-d][1, 4] diazepine, was established where Knoevenagel condensation of readily …
[1, 2-d][1, 4] diazepine, was established where Knoevenagel condensation of readily …