Advancing the logic of chemical synthesis: C− H activation as strategic and tactical disconnections for C− C bond construction
The design of synthetic routes by retrosynthetic logic is decisively influenced by the
transformations available. Transition‐metal‐catalyzed C− H activation has emerged as a …
transformations available. Transition‐metal‐catalyzed C− H activation has emerged as a …
Construction of sulfur-containing moieties in the total synthesis of natural products
N Wang, P Saidhareddy, X Jiang - Natural Product Reports, 2020 - pubs.rsc.org
Covering: January 2013 to September 2018 Sulfur-containing natural products are a large
class of significant functional molecules. Many of these compounds exhibit potent biological …
class of significant functional molecules. Many of these compounds exhibit potent biological …
Transfer of sulfur: from simple to diverse
H Liu, X Jiang - Chemistry–An Asian Journal, 2013 - Wiley Online Library
The introduction of sulfur atoms onto target molecules is an important area in organic
synthesis, in particular in the synthesis of pharmaceutical compounds, and a wide variety of …
synthesis, in particular in the synthesis of pharmaceutical compounds, and a wide variety of …
A brief history of antibiotics and select advances in their synthesis
The advent of modern antibiotics contributed enormously to the dramatic extension of
human lifespan since their discovery by virtue of their lethal and selective action against …
human lifespan since their discovery by virtue of their lethal and selective action against …
Marine natural products
Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 30, 237–323. This review covers
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …
[HTML][HTML] Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing
T Huo, X Zhao, Z Cheng, J Wei, M Zhu, X Dou… - … Pharmaceutica Sinica B, 2024 - Elsevier
Synthetic chemistry plays an indispensable role in drug discovery, contributing to hit
compounds identification, lead compounds optimization, candidate drugs preparation, and …
compounds identification, lead compounds optimization, candidate drugs preparation, and …
Electro‐oxidative S− H/S− H cross‐coupling with hydrogen evolution: facile access to unsymmetrical disulfides
Sulfur is an essential element because it exists widely in proteins. The disulfide bond is an
important moiety in many different types of significant organic molecules. A new approach …
important moiety in many different types of significant organic molecules. A new approach …
Photochemical route for synthesizing atomically precise metal nanoclusters from disulfide
ZM Zhu, Y Zhao, H Zhao, C Liu, Y Zhang, W Fei… - Nano Letters, 2023 - ACS Publications
Practical approaches to the synthesis of atomically precise metal nanoclusters are in high
demand as they provide the structural basis for investigating nanomaterials' structure …
demand as they provide the structural basis for investigating nanomaterials' structure …
New design of a disulfurating reagent: facile and straightforward pathway to unsymmetrical disulfanes by copper‐catalyzed oxidative cross‐coupling
A novel reagent, which introduces two sulfur atoms in one step, was designed and used for
the construction of diverse disulfanes by copper‐catalyzed oxidative cross‐coupling under …
the construction of diverse disulfanes by copper‐catalyzed oxidative cross‐coupling under …
Polysulfurating reagent design for unsymmetrical polysulfide construction
X **ao, J Xue, X Jiang - Nature communications, 2018 - nature.com
From life science to material science, to pharmaceutical industry, and to food chemistry,
polysulfides are vital structural scaffolds. However, there are limited synthetic methods for …
polysulfides are vital structural scaffolds. However, there are limited synthetic methods for …