Stealth and pseudo-stealth nanocarriers

P Wen, W Ke, A Dirisala, K Toh, M Tanaka… - Advanced drug delivery …, 2023 - Elsevier
The stealth effect plays a central role on capacitating nanomaterials for drug delivery
applications through improving the pharmacokinetics such as blood circulation …

Nanotechnology-based mRNA vaccines

S Chen, X Huang, Y Xue, E Álvarez-Benedicto… - Nature Reviews …, 2023 - nature.com
Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …

[HTML][HTML] Advances in chitosan-based nanoparticles for drug delivery

V Mikušová, P Mikuš - International journal of molecular sciences, 2021 - mdpi.com
Nanoparticles (NPs) have an outstanding position in pharmaceutical, biological, and
medical disciplines. Polymeric NPs based on chitosan (CS) can act as excellent drug …

Strategies to improve the EPR effect: a mechanistic perspective and clinical translation

M Ikeda-Imafuku, LLW Wang, D Rodrigues… - Journal of Controlled …, 2022 - Elsevier
Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …

Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Targeting strategies for tissue-specific drug delivery

Z Zhao, A Ukidve, J Kim, S Mitragotri - Cell, 2020 - cell.com
Off-target effects of systemically administered drugs have been a major hurdle in designing
therapies with desired efficacy and acceptable toxicity. Develo** targeting strategies to …

Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …

S Kansız, YM Elçin - Advances in Colloid and Interface Science, 2023 - Elsevier
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …

Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …

Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective

SA Ejazi, R Louisthelmy, K Maisel - ACS nano, 2023 - ACS Publications
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …