Pathogenesis and pathophysiology of idiopathic normal pressure hydrocephalus

Z Wang, Y Zhang, F Hu, J Ding… - CNS neuroscience & …, 2020 - Wiley Online Library
Idiopathic normal pressure hydrocephalus (iNPH), the most common type of adult‐onset
hydrocephalus, is a potentially reversible neuropsychiatric entity characterized by dilated …

Magnetic resonance elastography (MRE) of the human brain: technique, findings and clinical applications

LV Hiscox, CL Johnson, E Barnhill… - Physics in Medicine …, 2016 - iopscience.iop.org
Neurological disorders are one of the most important public health concerns in developed
countries. Established brain imaging techniques such as magnetic resonance imaging (MRI) …

Stiffness and beyond: what MR elastography can tell us about brain structure and function under physiologic and pathologic conditions

Z Yin, AJ Romano, A Manduca, RL Ehman… - Topics in Magnetic …, 2018 - journals.lww.com
Brain magnetic resonance elastography (MRE) was developed on the basis of a desire to
“palpate by imaging” and is becoming a powerful tool in the investigation of …

Physics of brain cancer: Multiscale alterations of glioblastoma cells under extracellular matrix stiffening

M Khoonkari, D Liang, M Kamperman, FAE Kruyt… - Pharmaceutics, 2022 - mdpi.com
The biology and physics underlying glioblastoma is not yet completely understood, resulting
in the limited efficacy of current clinical therapy. Recent studies have indicated the …

Viscoelasticity imaging of biological tissues and single cells using shear wave propagation

H Li, G Flé, M Bhatt, Z Qu, S Ghazavi, L Yazdani… - Frontiers in …, 2021 - frontiersin.org
Changes in biomechanical properties of biological soft tissues are often associated with
physiological dysfunctions. Since biological soft tissues are hydrated, viscoelasticity is likely …

MR elastography demonstrates unique regional brain stiffness patterns in dementias

M ElSheikh, A Arani, A Perry… - American Journal of …, 2017 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to investigate age-corrected brain MR
elastography (MRE) findings in four dementia cohorts (Alzheimer disease, dementia with …

Influence of age on global and regional brain stiffness in young and middle‐aged adults

T Takamura, U Motosugi, Y Sasaki… - Journal of Magnetic …, 2020 - Wiley Online Library
Background An understanding of potential age‐related changes in brain stiffness and its
regional variation is important for further clinical application of MR elastography. Purpose To …

Astrogliosis and impaired aquaporin‐4 and dystrophin systems in idiopathic normal pressure hydrocephalus

PK Eide, HA Hansson - Neuropathology and Applied …, 2018 - Wiley Online Library
Aims Idiopathic normal pressure hydrocephalus (iNPH) is one subtype of dementia that may
improve following drainage of cerebrospinal fluid (CSF). This prospective observational …

Intracranial pressure and intracranial elastance monitoring in neurocritical care

T Heldt, T Zoerle, D Teichmann… - Annual review of …, 2019 - annualreviews.org
Patients with acute brain injuries tend to be physiologically unstable and at risk of rapid and
potentially life-threatening decompensation due to shifts in intracranial compartment …

Identification of normal pressure hydrocephalus by disease-specific patterns of brain stiffness and dam** ratio

MC Murphy, PM Cogswell, JD Trzasko… - Investigative …, 2020 - journals.lww.com
Objectives The aim of this study was to perform a whole-brain analysis of alterations in brain
mechanical properties due to normal pressure hydrocephalus (NPH). Materials and …