Gene therapy represents a promising cancer treatment featuring high efficacy and limited
side effects, but it is stymied by a lack of safe and efficient gene-delivery vectors. Cationic …

Transfection by means of non-viral gene delivery vectors is the cornerstone of modern gene
delivery. Despite the resources poured into the development of ever more effective …

Natural killer (NK) cells participate in the immune system by eliminating cancer and virally
infected cells through germline-encoded surface receptors. Their independence from prior …

The production of proteins in appropriate quantity and quality is an essential requirement of
the present time. There appears to be a progressive increase in the application of …

Research models that replicate the diverse genetic and molecular landscape of breast
cancer are critical for develo** the next‐generation therapeutic entities that can target …

Upon receptor activation, the myeloid C‐type lectin receptor M incle signals via the S yk‐
CARD 9‐B cl10‐MALT 1 pathway. It does so by recruiting the ITAM‐bearing F cε RI‐γ. The …

An epidemic caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2)
spread globally in just a few months. To prevent the further spread of the virus, millions of …

Screening of new gene delivery candidates regarding transfection efficiency and toxicity is
usually performed by reading out transgene expression levels relative to a reference …

The introduction of foreign genetic material into cultured eukaryotic cells on a transient
basis, that is, by transfection, without selection for stable integration of plasmids into the host …

Advances in recombinant antibody technology and protein engineering have provided the
opportunity to reduce antibodies to their smallest binding domain components and have …