Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

AL Manson, KA Cohen, T Abeel, CA Desjardins… - Nature …, 2017 - nature.com
Multidrug-resistant tuberculosis (MDR-TB), caused by drug-resistant strains of
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …

Impact of antibiotic treatment and host innate immune pressure on enterococcal adaptation in the human bloodstream

D Van Tyne, AL Manson, MM Huycke… - Science translational …, 2019 - science.org
Multidrug-resistant enterococcal strains emerged in the early 1980s and are now among the
leading causes of drug-resistant bacterial infection worldwide. We used functional genomics …

Signatures of selection at drug resistance loci in Mycobacterium tuberculosis

TD Mortimer, AM Weber, CS Pepperell - MSystems, 2018 - Am Soc Microbiol
Tuberculosis (TB) is the leading cause of death by an infectious disease, and global TB
control efforts are increasingly threatened by drug resistance in Mycobacterium tuberculosis …

Highlights from the tenth ISCB student council symposium 2014

F Rahman, K Wilkins, A Jacobsen, A Junge, E Vicedo… - BMC …, 2015 - Springer
This report summarizes the scientific content and activities of the annual symposium
organized by the Student Council of the International Society for Computational Biology …