Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning?
Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …
Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection
Extended-spectrum β-lactamase (ESBL)-producing Gram-negative pathogens are a major
cause of resistance to expanded-spectrum β-lactam antibiotics. Since their discovery in the …
cause of resistance to expanded-spectrum β-lactam antibiotics. Since their discovery in the …
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis
Only a small proportion of patients with cancer show lasting responses to immune
checkpoint blockade (ICB)-based monotherapies. The RNA-editing enzyme ADAR1 is an …
checkpoint blockade (ICB)-based monotherapies. The RNA-editing enzyme ADAR1 is an …
Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost
The Omicron variant of SARS-CoV-2 infected many vaccinated and convalescent
individuals,–. Despite the reduced protection from infection, individuals who received three …
individuals,–. Despite the reduced protection from infection, individuals who received three …
Reduction of microbial diversity in grassland soil is driven by long-term climate warming
Anthropogenic climate change threatens ecosystem functioning. Soil biodiversity is essential
for maintaining the health of terrestrial systems, but how climate change affects the richness …
for maintaining the health of terrestrial systems, but how climate change affects the richness …
Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study
Antibody-based therapeutics and vaccines are essential to combat COVID-19 morbidity and
mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
Understanding the molecular basis for immune recognition of SARS-CoV-2 spike
glycoprotein antigenic sites will inform the development of improved therapeutics. We …
glycoprotein antigenic sites will inform the development of improved therapeutics. We …
Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine
V Oberhardt, H Luxenburger, J Kemming, I Schulien… - Nature, 2021 - nature.com
SARS-CoV-2 spike mRNA vaccines,–mediate protection from severe disease as early as ten
days after prime vaccination, when neutralizing antibodies are hardly detectable,–. Vaccine …
days after prime vaccination, when neutralizing antibodies are hardly detectable,–. Vaccine …
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
To combat future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …
Unravelling the collateral damage of antibiotics on gut bacteria
Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …