Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

A history of cyclodextrins

G Crini - Chemical reviews, 2014 - ACS Publications
Cyclodextrins (CDs) are synthetic substances obtained from the enzymatic degradation of
one of the most essential polysaccharides, starch. CDs belong to the family of cage …

Cyclodextrins as chiral selectors in capillary electrophoresis: Recent trends in mechanistic studies

B Chankvetadze, GKE Scriba - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
In the present review the potential of capillary electrophoresis for a better understanding of
the fine structural mechanisms of noncovalent interactions and enantioselective …

Structure control of polysaccharide derivatives for efficient separation of enantiomers by chromatography

T Ikai, Y Okamoto - Chemical Reviews, 2009 - ACS Publications
Chirality is a ubiquitous feature in living systems. Today, it is widely recognized that many
biologically interesting compounds, such as drugs, agrochemicals, food additives, and …

[HTML][HTML] New trends in the quality control of enantiomeric drugs: quality by design-compliant development of chiral capillary electrophoresis methods

S Orlandini, G Hancu, ZI Szabó, A Modroiu, LA Papp… - Molecules, 2022 - mdpi.com
Capillary electrophoresis (CE) is a potent method for analyzing chiral substances and is
commonly used in the enantioseparation and chiral purity control of pharmaceuticals from …

Native and substituted cyclodextrins as chiral selectors for capillary electrophoresis enantioseparations: Structures, features, application, and molecular modeling

P Peluso, B Chankvetadze - Electrophoresis, 2021 - Wiley Online Library
CDs are cyclic oligosaccharides consisting of α‐d‐glucopyranosyl units linked through 1, 4‐
linkages, which are obtained from enzymatic degradation of starch. The coexistence of …

High-performance liquid chromatographic enantioseparation of racemic drugs based on homochiral metal–organic framework

X Kuang, Y Ma, H Su, J Zhang, YB Dong… - Analytical …, 2014 - ACS Publications
Homochiral metal–organic frameworks with fine-tuned pore sizes/walls and large surface
areas are promising porous materials for enantioseparation considering the traditional …

Optically active polymers for chiral separation

C Yamamoto, Y Okamoto - Bulletin of the Chemical Society of …, 2004 - academic.oup.com
One of the most practically important functions of optically active polymers is chiral
recognition. In the past two decades, various optically active polymers have been utilized as …

Advances of capillary electrophoresis enantioseparations in pharmaceutical analysis (2017–2020)

S Krait, ML Konjaria, GKE Scriba - Electrophoresis, 2021 - Wiley Online Library
Capillary electrophoresis is a powerful technique for the analysis of polar chiral compounds
and has been widely accepted for analytical enantioseparations of drug compounds in …

Chiral separations

TJ Ward, DM Hamburg - Analytical Chemistry, 2004 - ACS Publications
This fundamental review article covers developments and applications in chiral separations
from January 2002 to January 2004 and is restricted to the English language literature. With …