Ischemic stroke is responsible for many deaths and long-term disability world wide.
Development of effective therapy has been the target of intense research. Accumulating …

Cells of the central nervous system were once thought to be incapable of regeneration. This
dogma has been challenged in the last decade with studies showing new, migrating stem …

The splenic response to stroke is a proinflammatory reaction to ischemic injury resulting in
expanded neurodegeneration. Splenectomy reduces neural injury in rodent models of …

Ischemic stroke remains one of most common causes of death and disability worldwide.
Stroke triggers a cascade of events leading to rapid neuronal damage and death …

Endothelial progenitor cells (EPCs) seem to be a promising option to treat patients with
ischemic diseases. Here, we investigated the effects of late outgrowth EPCs, or endothelial …

Stroke is a leading cause of death in the US and around the world but with limited treatment
options. Survivors often present with long-term cognitive and neurological deficits. Stem cell …

There is a compelling need to develop cell and pharmacological therapeutic approaches to
be administered beyond the hyperacute phase of stroke. These therapies capitalize on the …

Recent studies have highlighted the involvement of the peripheral immune system in
delayed cellular degeneration after stroke. In the permanent middle cerebral artery …

Mesenchymal stromal cells (MSCs) are promising candidates for develo** cell therapies
for intractable diseases. To assess the feasibility of transplantation with human umbilical …

Background and Purpose—Systemic injection of hematopoietic stem cells after ischemic
cardiac or neural lesions is one approach to promote tissue repair. However, mechanisms of …