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Experimental models and methods for cutaneous wound healing assessment
Wound healing studies are intricate, mainly because of the multifaceted nature of the wound
environment and the complexity of the healing process, which integrates a variety of cells …
environment and the complexity of the healing process, which integrates a variety of cells …
Challenges in the treatment of chronic wounds
RG Frykberg, J Banks - Advances in wound care, 2015 - liebertpub.com
Significance: Chronic wounds include, but are not limited, to diabetic foot ulcers, venous leg
ulcers, and pressure ulcers. They are a challenge to wound care professionals and …
ulcers, and pressure ulcers. They are a challenge to wound care professionals and …
Oxygen in acute and chronic wound healing
S Schreml, RM Szeimies, L Prantl… - British Journal of …, 2010 - academic.oup.com
Oxygen is a prerequisite for successful wound healing due to the increased demand for
reparative processes such as cell proliferation, bacterial defence, angiogenesis and …
reparative processes such as cell proliferation, bacterial defence, angiogenesis and …
Hypoxia: molecular pathophysiological mechanisms in human diseases
Hypoxia, a low O2 tension, is a fundamental feature that occurs in physiological events as
well as pathophysiological conditions, especially mentioned for its role in the mechanism of …
well as pathophysiological conditions, especially mentioned for its role in the mechanism of …
Wound healing essentials: let there be oxygen
The state of wound oxygenation is a key determinant of healing outcomes. From a
diagnostic standpoint, measurements of wound oxygenation are commonly used to guide …
diagnostic standpoint, measurements of wound oxygenation are commonly used to guide …
The role of oxygen in wound healing: a review of the literature
PG Rodriguez, FN Felix, DT Woodley… - Dermatologic …, 2008 - journals.lww.com
Dermatologic Surgery Log in or Register Get new issue alertsGet alerts Subscribe to journal
Secondary Logo Journal Logo Advanced Search Toggle navigation Register Login Articles & …
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[HTML][HTML] Topical wound oxygen therapy in the treatment of chronic diabetic foot ulcers
RG Frykberg - Medicina, 2021 - mdpi.com
Oxygen is a critical component of many biological processes and is essential for wound
healing. Chronic wounds are typically characterized as being hypoxic in that the partial …
healing. Chronic wounds are typically characterized as being hypoxic in that the partial …
Efficacy of topical wound oxygen therapy in healing chronic diabetic foot ulcers: systematic review and meta-analysis
Objective: To conduct a systematic review and meta-analysis of recently published
randomized controlled trials (RCTs) that employed the use of topical oxygen therapy (TOT) …
randomized controlled trials (RCTs) that employed the use of topical oxygen therapy (TOT) …
A multinational, multicenter, randomized, double-blinded, placebo-controlled trial to evaluate the efficacy of cyclical topical wound oxygen (TWO2) therapy in the …
OBJECTIVE Topical oxygen has been used for the treatment of chronic wounds for more
than 50 years. Its effectiveness remains disputed due to the limited number of robust high …
than 50 years. Its effectiveness remains disputed due to the limited number of robust high …
Aerobically Derived Lactate Stimulates Revascularization and Tissue Repair via Redox Mechanisms
TK Hunt, RS Aslam, S Beckert, S Wagner… - Antioxidants & redox …, 2007 - liebertpub.com
Hypoxia serves as a physiologic cue to drive an angiogenic response via HIF-dependent
mechanisms. Interestingly, minor elevation of lactate levels in the tissue produces the same …
mechanisms. Interestingly, minor elevation of lactate levels in the tissue produces the same …