Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes with potent immunosuppressive activity. They are implicated in the regulation of …

Abstract Cyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers
exerting a pleiotropic and multifaceted role in genesis or promotion of carcinogenesis and …

Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

Epstein-Barr virus (EBV), a gamma-1 herpesvirus, is carried as a life-long asymptomatic
infection by the great majority of individuals in all human populations. Yet this seemingly …

This review discusses the current state of the viral metabolism field and gaps in knowledge
that will be important for future studies to investigate. We discuss metabolic rewiring caused …

EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …

The general immune landscape of nasopharyngeal carcinoma (NPC) renders
immunotherapy suitable for patients with NPC. Immune checkpoint inhibitors (ICIs) based on …

Objective Hepatocellular carcinoma (HCC), mostly developed in fibrotic/cirrhotic liver,
exhibits relatively low responsiveness to immune checkpoint blockade (ICB) therapy. As …

The Epstein-Barr virus (EBV) is a ubiquitous human pathogen linked to various diseases,
including infectious mononucleosis and multiple types of cancer. To control and eliminate …

T cell exhaustion is an obstacle to immunotherapy for solid tumors. An understanding of the
mechanism by which T cells develop this phenotype in solid tumors is needed. Here …