[HTML][HTML] Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Y Ju, Y Hu, P Yang, X **e, B Fang - Materials Today Bio, 2023 - Elsevier
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

Exosomes: large-scale production, isolation, drug loading efficiency, and biodistribution and uptake

I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …

New strategies of neurodegenerative disease treatment with extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs)

CP Palanisamy, JJ Pei, P Alugoju… - …, 2023 - pmc.ncbi.nlm.nih.gov
Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …

[HTML][HTML] Methods of the large-scale production of extracellular vesicles

V Syromiatnikova, A Prokopeva… - International journal of …, 2022 - mdpi.com
To date, extracellular vesicles (EVs) have been extensively investigated as potential
substitutes for cell therapy. Research has suggested their ability to overcome serious risks …

Extracellular vesicle heterogeneity and its impact for regenerative medicine applications

SI Van De Wakker, FM Meijers, JPG Sluijter… - Pharmacological …, 2023 - Elsevier
Extracellular vesicles (EVs) are cell-derived membrane-enclosed particles that are involved
in physiologic and pathologic processes. EVs are increasingly being studied for therapeutic …

[HTML][HTML] Scalable production of extracellular vesicles and its therapeutic values: a review

CY Ng, LT Kee, ME Al-Masawa, QH Lee… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

SM Davidson, CM Boulanger, E Aikawa… - Cardiovascular …, 2023 - academic.oup.com
Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from
cells of the cardiovascular system, and are considered important mediators of intercellular …

Technological advances towards extracellular vesicles mass production

A Grangier, J Branchu, J Volatron, M Piffoux… - Advanced Drug Delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are becoming essential actors in bio-therapeutics, as much for
their regenerative or immunomodulatory properties as for their potential as cargo delivery …

The discovery of extracellular vesicles and their emergence as a next-generation therapy

A Rai, B Claridge, J Lozano, DW Greening - Circulation research, 2024 - ahajournals.org
From their humble discovery as cellular debris to cementing their natural capacity to transfer
functional molecules between cells, the long-winded journey of extracellular vesicles (EVs) …

Heterogeneity of mesenchymal stem cell-derived extracellular vesicles is highly impacted by the tissue/cell source and culture conditions

C Almeria, S Kreß, V Weber, D Egger, C Kasper - Cell & Bioscience, 2022 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures exerting major effects in
physiological as well as pathological processes by functioning as vehicles for the delivery of …