Advances and challenges in intranasal delivery of antipsychotic agents targeting the central nervous system

M Pandey, N Jain, J Kanoujia, Z Hussain… - Frontiers in …, 2022 - frontiersin.org
Treatment of central nervous system (CNS) disorders is challenging using conventional
delivery strategies and routes of administration because of the presence of the blood–brain …

[HTML][HTML] On the mucoadhesive properties of synthetic and natural polyampholytes

M Fu, SK Filippov, AC Williams… - Journal of Colloid and …, 2024 - Elsevier
Hypothesis The mucoadhesive characteristics of amphoteric polymers (also known as
polyampholytes) can vary and are influenced by factors such as the solution's pH and its …

Exploring the physicochemical interactions and loading strategies of mesoporous silicon dioxide nanoparticles for drug delivery

SY Kovtareva, EE Kopishev, H Zhang… - European Journal of …, 2025 - Elsevier
Mesoporous silica nanoparticles play an important role in drug delivery due to their high
surface area, porous structure, tunable pore size, chemical stability and functionalization …

Cataleptogenic effect of haloperidol formulated in water-soluble calixarene-based nanoparticles

NE Kashapova, RR Kashapov, AY Ziganshina… - Pharmaceutics, 2023 - mdpi.com
In this study, a water-soluble form of haloperidol was obtained by coaggregation with calix
[4] resorcinol bearing viologen groups on the upper rim and decyl chains on the lower rim to …

PVA-based formulations as a design-technology platform for orally disintegrating film matrices

M Kozakiewicz-Latała, AJ Dyba, D Marciniak… - International Journal of …, 2024 - Elsevier
In the majority of pharmaceutical applications, polymers are employed extensively in a
diverse range of pharmaceutical products, serving as indispensable components of …

Advancement in the nose-to-brain drug delivery of FDA-approved drugs for the better management of depression and psychiatric disorders

R Upadhyay, P Ghosh, M Desavathu - International Journal of …, 2024 - Elsevier
Abstract The Prevalence of Depressive and Psychiatric disorders is increasing globally, and
despite the availability of numerous FDA-approved drugs, treatment remains challenging …

[PDF][PDF] Characterization of promising smart nanopolymers that release drugs in response to illness-related signals: a review

NH Aysa, LF Aljibouri, RS Almuttairi - 2024 - pharmakonpress.gr
Smart nanopolymers with the capability to release drugs on demand and in response to
specific illness signals, represent a promising avenue in the field of drug delivery. Their …