Evaluation and management of hypernatremia in adults: clinical perspectives

G Yun, SH Baek, S Kim - The Korean Journal of Internal …, 2022 - pmc.ncbi.nlm.nih.gov
Hypernatremia is an occasionally encountered electrolyte disorder, which may lead to fatal
consequences under improper management. Hypernatremia is a disorder of the …

Dysnatremia in a changing climate: A global systematic review of the association between serum sodium and ambient temperature

E Wootton, M Grossmann, AM Warren - Clinical Endocrinology, 2024 - Wiley Online Library
Objective Both hyponatremia and hypernatremia have been reported to occur more
frequently with higher ambient temperatures, although the underlying mechanisms are not …

Salt and water: a review of hypernatremia

N Patel, D Patel, SS Farouk, JL Rein - Advances in Kidney Disease and …, 2023 - Elsevier
Serum sodium disorders are generally a marker of water balance in the body. Thus,
hypernatremia is most often caused by an overall deficit of total body water. Other unique …

[HTML][HTML] Efficacy and safety of hydrocortisone, ascorbic acid, and thiamine combination therapy for the management of sepsis and septic shock: a systematic review …

J Deng, QK Zuo, K Venugopal, J Hung… - … Archives of Allergy and …, 2024 - karger.com
Introduction: This systematic review aimed to assess the efficacy and safety of
hydrocortisone, ascorbic acid, and thiamine (HAT) combination therapy in patients with …

Systematic review and meta-analysis of the treatment of hypernatremia in adult hospitalized patients: impact on mortality, morbidity, and treatment-related side effects

N Kitisin, N Raykateeraroj, Y Hikasa, L Bianchini… - Journal of Critical …, 2025 - Elsevier
Background Hypernatremia is relatively common in acutely ill patients and associated with
mortality. Guidelines recommend a slow rate of correction (≤ 0.5 mmol/L per hour) …

Diagnostic validity and solute-corrected prevalence for hyponatremia and hypernatremia among 1 813 356 admissions

A Okada, H Yamana, H Watanabe… - Clinical Kidney …, 2024 - academic.oup.com
Background and hypothesis We aimed to evaluate the diagnostic validity of the International
Classification of Diseases, 10th Revision (ICD-10) codes for hyponatremia and …

Acute kidney injury with hypernatremia and major adverse kidney events

JJ Zaragoza, JA Gómez-Fregoso… - Clinical Kidney …, 2025 - academic.oup.com
Introduction Consequences of hypernatremia in akute kidney injury (AKI-hyperNa) is poorly
understood. We analyzed the risk of major adverse kidney events (MAKE) in comparison …

[HTML][HTML] In-hospital hypernatremia prior to discharge to primary care hospitals predicts 90-day mortality in older hip fracture patients

LM Pehkonen, S Collin, P Korhonen, MS Nuotio - Injury, 2025 - Elsevier
Purpose Discharge is a critical time point in the care pathway of geriatric hospital patients,
and post-acute care facilities often have less monitoring possibilities. Active medical issues …

Electrolyte Disorders: Causes, Diagnosis, and Initial Care—Part 2

NJ Larson, FB Rogers, JL Feeken… - Air Medical …, 2024 - airmedicaljournal.com
Sodium (Na+) is the most common extracellular cation in the body, the second most
common intracellular cation, and the principal electrolyte in maintaining osmolarity. The Na+ …

Systemic and iatrogenic factors contribute to the development of severe hypernatraemia in vulnerable inpatients

E Kathpal, E Boehm, CS Nguyen, S Vogrin… - Clinical …, 2024 - Wiley Online Library
Objectives To determine all‐cause in‐hospital mortality associated with severe
hypernatraemia and the causes, comorbidities, time to treatment, discharge destination and …