Analytical approaches for determination of COVID-19 candidate drugs in human biological matrices

R Mahdavi, Z Talebpour - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Since the outbreak of the COVID-19 pandemic, the use of antiviral and other available drugs
has been considered to combat or reduce the clinical symptoms of patients. In this regard, it …

Electroanalytical methods for determination of antiviral drugs in pharmaceutical formulation and biological fluids: A review

Z AYDOĞMUŞ, A Asfoor - Chinese Journal of Analytical Chemistry, 2022 - Elsevier
Viruses can infect all kinds of life forms, from humans, animals and plants to
microorganisms, including bacteria and archaea, and can cause serious illness, including a …

[HTML][HTML] Simultaneous determination of favipiravir and surrogates of its metabolites by means of heart-cutting bidimensional liquid chromatography (2D-LC)

A Sánchez-Hernández, D García-Gómez… - Analytical …, 2024 - Elsevier
Therapeutic monitoring of drugs, particularly those with multiple metabolites, can be time-
consuming and labor-intensive due to the need for different analytical methods depending …

Nanomaterial-Based Electrochemical Sensors for Anti-HIV Drug Monitoring: Innovations, Challenges, and Prospects

AA Lahcen, G Slaughter - Journal of Pharmaceutical and Biomedical …, 2025 - Elsevier
Monitoring human immunodeficiency virus (HIV) and anti-HIV drugs is critical for optimizing
treatment outcomes and preventing drug resistance. Accurate detection and quantification of …

[PDF][PDF] Development and Validation of Analytical Procedures for the Simultaneous Estimation of Acyclovir and Zidovudine through UV and RP-HPLC Methods

J Chundur, PK Chadalawada, GK Babu… - World Journal of …, 2024 - researchgate.net
Combinatorial therapy involving Acyclovir and Zidovudine treats herpes-infected
immunocompromised patients, offering enhanced efficacy and reduced risk of drug …

Assessment of Analytical Techniques for Precise Quantification of Four Antiviral Drugs in Pharmaceutical Research and Development: A Comprehensive Review

A Gupta, S Pathak - Current Pharmaceutical Analysis, 2024 - benthamdirect.com
Precise measurement of drug concentration in pharmaceutical research is critical, especially
for anti-viral drugs like boceprevir, elvitegravir, indinavir, and saquinavir that combat viral …

LC–MS/MS separation and quantitation of ribavirin in chicken and comparison of different mass spectrometric platforms

D Xu, H Huang, W Hu, X Liu, J Yang - BMC chemistry, 2023 - Springer
A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed
for the analysis of ribavirin in chicken. Samples was extracted with 0.1% formic acid and …

Analytical profiling of sofosbuvir as NS5B protein inhibitor for oral drug delivery: Method development and Validation

SW Rangari, SB Bari - Bulletin of Faculty of Pharmacy Cairo …, 2022 - bfopcu.eg.net
Hepatitis C virus (HCV) non-structural protein 5B (NS5B), which is being studied for its RNA-
dependent RNA polymerase (RDRP). It has been demonstrated that the RDRP is highly …

Advanced oxidation processes for degradation of pharmaceuticals used during COVID-19 pandemic

I Ramirez, E Mariam, A Kumar, D Yanardağ… - … for Remediation of …, 2024 - Elsevier
The COVID-19 pandemic impacted public health, the economy, and the environment
worldwide. During the pandemic, high demand for prescribed pharmaceuticals to treat …

Electrochemical determination of antiviral drug Famciclovir in human serum samples at boron-doped diamond electrode

ÇK Dindar - Turkish Journal of Analytical Chemistry, 2022 - dergipark.org.tr
The electrochemical oxidation of famciclovir was investigated in pH range 2.0-10.0 using
differential pulse voltammetry at boron-doped diamond electrode. The experimental results …