Optoacoustic imaging of the skin

XL Deán‐Ben, D Razansky - Experimental dermatology, 2021 - Wiley Online Library
Optoacoustic (OA, photoacoustic) imaging capitalizes on the synergistic combination of light
excitation and ultrasound detection to empower biological and clinical investigations with …

How is depth of anaesthesia assessed in experimental pigs? A sco** review

A Mirra, E Gamez Maidanskaia, LP Carmo… - Plos one, 2023 - journals.plos.org
Background Despite the large number of pigs involved in translational studies, no gold
standard depth of anaesthesia indicators are available. We undertook a sco** review to …

Integrating single‐cell and spatial transcriptomics reveals heterogeneity of early pig skin development and a subpopulation with hair placode formation

Y Wang, Y Jiang, G Ni, S Li, B Balderson… - Advanced …, 2024 - Wiley Online Library
The dermis and epidermis, crucial structural layers of the skin, encompass appendages, hair
follicles (HFs), and intricate cellular heterogeneity. However, an integrated spatiotemporal …

Natural NADH and FAD autofluorescence as label-free biomarkers for discriminating subtypes and functional states of immune cells

S Lemire, OM Thoma, L Kreiss, S Völkl… - International journal of …, 2022 - mdpi.com
Immune cell activity is a major factor for disease progression in inflammatory bowel diseases
(IBD). Classifying the type and functional state of immune cells is therefore crucial in clinical …

Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics

RR Iyer, JE Sorrells, L Yang, EJ Chaney… - Scientific reports, 2022 - nature.com
Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet,
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …

[HTML][HTML] Seeing through the skin: Optical methods for visualizing transdermal drug delivery with microneedles

B Limcharoen, S Wanichwecharungruang… - Advanced Drug Delivery …, 2024 - Elsevier
Optical methods play a pivotal role in advancing transdermal drug delivery research,
particularly with the emergence of microneedle technology. This review presents a …

Single-photon peak event detection (SPEED): a computational method for fast photon counting in fluorescence lifetime imaging microscopy

JE Sorrells, RR Iyer, L Yang, EJ Chaney… - Optics …, 2021 - opg.optica.org
Fluorescence lifetime imaging microscopy (FLIM) characterizes samples by examining the
temporal properties of fluorescence emission, providing useful contrast within samples …

Real-time pixelwise phasor analysis for video-rate two-photon fluorescence lifetime imaging microscopy

JE Sorrells, RR Iyer, L Yang, AJ Bower… - Biomedical optics …, 2021 - opg.optica.org
Two-photon fluorescence lifetime imaging microscopy (FLIM) is a widely used technique in
biomedical optical imaging. Presently, many two-photon time-domain FLIM setups are …

A multimodal nonlinear optical microscopy study of the responses of Pseudomonas aeruginosa to blue light and antibiotic treatment

C Zhang, FR Zaki, J Won, SA Boppart - Journal of Biophotonics, 2024 - Wiley Online Library
Pseudomonas aeruginosa (P. aeruginosa) is a multidrug‐resistant human pathogen
involved in numerous infections. Understanding the response of P. aeruginosa to various …

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

QK Anjani, AR Johnson, AH Sabri… - Advanced …, 2025 - Wiley Online Library
This research focuses on develo** and characterizing islatravir‐loaded dissolving
microarray patches (MAPs) to provide an effective, minimally invasive treatment option for …