[HTML][HTML] Advancements in precision nanomedicine design targeting the anoikis-platelet interface of circulating tumor cells

M Tang, Z Zhang, P Wang, F Zhao, L Miao… - … Pharmaceutica Sinica B, 2024 - Elsevier
Tumor metastasis, the apex of cancer progression, poses a formidable challenge in
therapeutic endeavors. Circulating tumor cells (CTCs), resilient entities originating from …

Advances in autophagy as a target in the treatment of tumours

Y Li, S Gao, X Du, J Ji, Y **, G Zhai - Journal of Drug Targeting, 2022 - Taylor & Francis
Autophagy is a multi-step lysosomal degradation process, which regulates energy and
material metabolism and has been used to maintain homeostasis. Autophagy has been …

Clearing Properties Between Coconut Oil and Xylene in Histological Tissue Processing

OA Bright, DN Samuel, MA Adisa… - … of Histochemistry & …, 2024 - journals.sagepub.com
Xylene is the commonest clearing agent even though it is hazardous and costly. This study
evaluated the clearing properties of coconut oil as an alternative cost-effective clearing …

Reduced DAPK1 expression promotes stem cell-like characteristics of prostate cancer cells by activating ZEB1 via Hippo/YAP signaling pathway

S Nong, Z Wei, Z Wang, L Ma, Y Guan… - Stem Cells and …, 2021 - liebertpub.com
Prostate cancer (PCa) is a malignant tumor that originates in the male genitourinary system.
Downregulation of death-associated protein kinase 1 (DAPK1) is closely related to PCa …

Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon

K Shah, B Guo, SC Hicks - bioRxiv, 2024 - biorxiv.org
An important task in the analysis of spatially resolved transcriptomics data is to identify
spatially variable genes (SVGs), or genes that vary in a 2D space. Current approaches rank …

A review on the impact of aberrant methylation in breast cancer: diagnostic, prognostic, and therapeutic approaches

M Hosseini, S Feghhi-Najafabadi… - Iranian Journal of …, 2024 - ijbiotech.com
Breast cancer (BC) is still a major global health concern, and a key factor in its
pathophysiology is epigenetic abnormalities, specifically DNA methylation and histone …

Dapk1 promoted inflammation of infantile pneumonia by p38MAPK/NF-κB signaling pathway

W Zhang - Molecular & Cellular Toxicology, 2021 - Springer
Background The present study was designed to investigate the function of death-associated
protein kinase 1 (DAPK1) in infantile pneumonia and explore the potential mechanism of the …

Transfer Learning Based Approaches for Breast Cancer Classification using Mammogram Images

M Sharifujjaman, Z Ferdousee… - … on Computer and …, 2023 - ieeexplore.ieee.org
Breast cancer is a growing epidemic and a leading cause of death among women
worldwide. Mammographic imaging has been found to be highly effective in detecting breast …

[PDF][PDF] Antitumor potential of aqueous leaf extract of Leucocasia gigantea (Blume.) Schott in breast cancer metastasis

V Bindu, SN Deshpande, PSR Dwivedi… - Annals of …, 2023 - researchgate.net
One of the crucial components of cancer is metastasis, which spreads from the site of origin
to a different portion of the body. Prior studies on the plant have shown that the medicinal …

[PDF][PDF] Serum Lactate Dehydrogenase as a potential predictive index of chemotherapy response in breast cancer patients

GK Aryee, B Arko-Boham, NEB Antwi, J Nsaful… - Health Sciences …, 2024 - ajol.info
Background: Monitoring treatment during breast cancer management is crucial. Lactate
dehydrogenase (LDH) expression and activity drive cancer progression through metabolic …