Regulation of intestinal lipid metabolism: current concepts and relevance to disease

CW Ko, J Qu, DD Black, P Tso - Nature Reviews Gastroenterology & …, 2020 - nature.com
Lipids entering the gastrointestinal tract include dietary lipids (triacylglycerols, cholesteryl
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …

Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease

TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …

Gut microbiota‐derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity

LG Hersoug, P Møller, S Loft - Obesity Reviews, 2016 - Wiley Online Library
The composition of the gut microbiota and excessive ingestion of high‐fat diets (HFD) are
considered to be important factors for development of obesity. In this review we describe a …

Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism

MY Pepino, O Kuda, D Samovski… - Annual review of …, 2014 - annualreviews.org
CD36 (cluster of differentiation 36) is a scavenger receptor that functions in high-affinity
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …

Chylomicrons promote intestinal absorption of lipopolysaccharides

S Ghoshal, J Witta, J Zhong, W De Villiers… - Journal of lipid …, 2009 - jlr.org
Recent data suggest that dietary fat promotes intestinal absorption of lipopolysaccharides
(LPS) from the gut microflora, which might contribute to various inflammatory disorders. The …

Carotenoid metabolism at the intestinal barrier

J von Lintig, J Moon, J Lee, S Ramkumar - Biochimica et Biophysica Acta …, 2020 - Elsevier
Carotenoids exert a rich variety of physiological functions in mammals and are beneficial for
human health. These lipids are acquired from the diet and metabolized to apocarotenoids …

Absorption of vitamin A and carotenoids by the enterocyte: focus on transport proteins

E Reboul - Nutrients, 2013 - mdpi.com
Vitamin A deficiency is a public health problem in most develo** countries, especially in
children and pregnant women. It is thus a priority in health policy to improve preformed …

Role of the gut in lipid homeostasis

NA Abumrad, NO Davidson - Physiological reviews, 2012 - journals.physiology.org
Intestinal lipid transport plays a central role in fat homeostasis. Here we review the pathways
regulating intestinal absorption and delivery of dietary and biliary lipid substrates, principally …

Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation

M Guerville, G Boudry - American Journal of Physiology …, 2016 - journals.physiology.org
The human microbiota consists of 100 trillion microorganisms that provide important
metabolic and biological functions benefiting the host. However, the presence in host …

Diet-induced gut dysbiosis and inflammation: Key drivers of obesity-driven NASH

GG Kang, NL Trevaskis, AJ Murphy, MA Febbraio - Iscience, 2023 - cell.com
Sucrose, the primary circulating sugar in plants, contains equal amounts of fructose and
glucose. The latter is the predominant circulating sugar in animals and thus the primary fuel …