Neutrophil gelatinase–associated lipocalin (NGAL) is expressed and secreted by immune
cells, hepatocytes, and renal tubular cells in various pathologic states. NGAL exerts …

The mammalian kidney, the metanephros, is a mesodermal organ classically regarded as
arising from the intermediate mesoderm (IM). Indeed, both the ureteric bud (UB), which gives …

Background Current management of AKI, a potentially fatal disorder that can also initiate or
exacerbate CKD, is merely supportive. Therefore, deeper understanding of the molecular …

Adult human stem cells are employed in novel treatments and bio-artificial devices. Recent
studies have identified an abundant source of stem cells termed adipose-derived adult stem …

Abstract In late 2004, an International Consortium of research groups were charged with the
task of producing a high-quality molecular anatomy of the develo** mammalian urogenital …

Bone marrow–and adult kidney–derived stem/progenitor cells hold promise in the
development of therapies for renal failure. Here is reported the identification and …

The development of the human kidney is a complex process that requires interactions
between epithelial and mesenchymal cells, eventually leading to the coordinated growth …

Renal failure has a high prevalence and is becoming a public health problem worldwide.
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …

Regenerative medicine is being heralded in a similar way as gene therapy was some 15 yr
ago. It is an area of intense excitement and potential, as well as myth and disinformation …

Acute kidney injury (AKI) is one of the most relevant health issues, leading to millions of
deaths. The magnitude of the phenomenon remarks the urgent need for innovative and …