Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson… - Breast Cancer …, 2013 - Springer
Introduction Breast cancer remains a significant scientific, clinical and societal challenge.
This gap analysis has reviewed and critically assessed enduring issues and new challenges …
This gap analysis has reviewed and critically assessed enduring issues and new challenges …
Aromatase inhibitor-associated musculoskeletal syndrome: understanding mechanisms and management
T Hyder, CC Marino, S Ahmad… - Frontiers in …, 2021 - frontiersin.org
Aromatase inhibitors (AIs) are a key component in the chemoprevention and treatment of
hormone receptor-positive (HR+) breast cancer. While the addition of AI therapy has …
hormone receptor-positive (HR+) breast cancer. While the addition of AI therapy has …
17β-hydroxysteroid dehydrogenases in the progression of nonalcoholic fatty liver disease
MX Wang, ZG Peng - Pharmacology & Therapeutics, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has become a worldwide epidemic and a major
public health problem, with a prevalence of approximately 25%. The pathogenesis of …
public health problem, with a prevalence of approximately 25%. The pathogenesis of …
Transdermal delivery of chemotherapeutics: Strategies, requirements, and opportunities
Chemotherapeutic drugs are primarily administered to cancer patients via oral or parenteral
routes. The use of transdermal drug delivery could potentially be a better alternative to …
routes. The use of transdermal drug delivery could potentially be a better alternative to …
Understanding landmarking and its relation with time-dependent Cox regression
Time-dependent Cox regression and landmarking are the two most commonly used
approaches for the analysis of time-dependent covariates in time-to-event data. The …
approaches for the analysis of time-dependent covariates in time-to-event data. The …
[HTML][HTML] Is it best to expect the worst? Influence of patients' side-effect expectations on endocrine treatment outcome in a 2-year prospective clinical cohort study
Background This study aims to determine the role of patient expectations as potentially
modifiable factor of side-effects, quality of life, and adherence to endocrine treatment of …
modifiable factor of side-effects, quality of life, and adherence to endocrine treatment of …
Prognostic significance of adverse events in patients with hepatocellular carcinoma treated with sorafenib
A Granito, S Marinelli, G Negrini… - Therapeutic …, 2016 - journals.sagepub.com
Sorafenib is the standard treatment for patients with hepatocellular carcinoma (HCC) with
advanced stage disease. Although its effectiveness has been demonstrated by randomized …
advanced stage disease. Although its effectiveness has been demonstrated by randomized …
Status of adjuvant endocrine therapy for breast cancer
G Schiavon, IE Smith - Breast Cancer Research, 2014 - Springer
Adjuvant endocrine therapy reduces the risk of recurrence and death from breast cancer in
women with hormone receptor-positive early breast cancer. Tamoxifen has been the …
women with hormone receptor-positive early breast cancer. Tamoxifen has been the …
Cancer of the breast
Breast cancer is the most frequently diagnosed cancer in women in the United States, with a
lifetime risk of 1 in 8. Age, family history, and exposure to hormones affect risk of develo** …
lifetime risk of 1 in 8. Age, family history, and exposure to hormones affect risk of develo** …
Aromatase inhibitor induced musculoskeletal syndrome: a significant problem with limited treatment options
JM Lombard, N Zdenkowski, K Wells… - Supportive Care in …, 2016 - Springer
Background Aromatase inhibitor induced musculoskeletal syndrome is experienced by
approximately half of women taking aromatase inhibitors, impairing quality of life and …
approximately half of women taking aromatase inhibitors, impairing quality of life and …