A review of theranostics: perspectives on emerging approaches and clinical advancements

BJ Burkett, DJ Bartlett, PW McGarrah… - Radiology: Imaging …, 2023‏ - pubs.rsna.org
Theranostics is the combination of two approaches—diagnostics and therapeutics—applied
for decades in cancer imaging using radiopharmaceuticals or paired radiopharmaceuticals …

Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022‏ - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

[HTML][HTML] Overview of the most promising radionuclides for targeted alpha therapy: The “hopeful eight”

R Eychenne, M Chérel, F Haddad, F Guérard… - Pharmaceutics, 2021‏ - mdpi.com
Among all existing radionuclides, only a few are of interest for therapeutic applications and
more specifically for targeted alpha therapy (TAT). From this selection, actinium-225 …

[HTML][HTML] Radiopharmaceutical treatments for cancer therapy, radionuclides characteristics, applications, and challenges

S Salih, A Alkatheeri, W Alomaim, A Elliyanti - Molecules, 2022‏ - mdpi.com
Advances in the field of molecular biology have had an impact on biomedical applications,
which provide greater hope for both imaging and therapeutics. Work has been intensified on …

Transforming nuclear medicine with nanoradiopharmaceuticals

I Roy, S Krishnan, AV Kabashin, IN Zavestovskaya… - ACS …, 2022‏ - ACS Publications
Nuclear medicine is expected to make major advances in cancer diagnosis and therapy;
tumor-targeted radiopharmaceuticals preferentially eradicate tumors while causing minimal …

Radiolabeled nanomaterial for cancer diagnostics and therapeutics: Principles and concepts

M Goel, Y Mackeyev, S Krishnan - Cancer Nanotechnology, 2023‏ - Springer
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer
diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora …

Targeted alpha therapy, an emerging class of cancer agents: a review

C Parker, V Lewington, N Shore, C Kratochwil… - JAMA …, 2018‏ - jamanetwork.com
Importance Targeted alpha therapy attempts to deliver systemic radiation selectively to
cancer cells while minimizing systemic toxic effects and may lead to additional treatment …

Targeted radionuclide therapy of human tumors

SV Gudkov, NY Shilyagina, VA Vodeneev… - International journal of …, 2015‏ - mdpi.com
Targeted radionuclide therapy is one of the most intensively develo** directions of nuclear
medicine. Unlike conventional external beam therapy, the targeted radionuclide therapy …

Actinium-225 for targeted α therapy: coordination chemistry and current chelation approaches

NA Thiele, JJ Wilson - Cancer biotherapy & radiopharmaceuticals, 2018‏ - liebertpub.com
The α-emitting radionuclide actinium-225 possesses nuclear properties that are highly
promising for use in targeted α therapy (TAT), a therapeutic strategy that employs α particle …

Alpha-peptide receptor radionuclide therapy using actinium-225 labeled somatostatin receptor agonists and antagonists

M Shi, V Jakobsson, L Greifenstein, PL Khong… - Frontiers in …, 2022‏ - frontiersin.org
Peptide receptor radionuclide therapy (PRRT) has over the last two decades emerged as a
very promising approach to treat neuroendocrine tumors (NETs) with rapidly expanding …