Targeting the tumor microenvironment with biomaterials for enhanced immunotherapeutic efficacy
Y Feng, Q Tang, B Wang, Q Yang, Y Zhang… - Journal of …, 2024 - Springer
The tumor microenvironment (TME) is a complex system characterized by low oxygen, low
pH, high pressure, and numerous growth factors and protein hydrolases that regulate a wide …
pH, high pressure, and numerous growth factors and protein hydrolases that regulate a wide …
Nitric oxide-based multi-synergistic nanomedicine: An emerging therapeutic for anticancer
Y Tang, Q Li, Z Zhou, H Bai, N **ao, J **e… - Journal of …, 2024 - Springer
Gas therapy has emerged as a promising approach for treating cancer, with gases like NO,
H2S, and CO showing positive effects. Among these, NO is considered a key gas molecule …
H2S, and CO showing positive effects. Among these, NO is considered a key gas molecule …
Optogenetically engineered Septin-7 enhances immune cell infiltration of tumor spheroids
J Chen, B Hnath, CM Sha, L Beidler, TD Schell… - Proceedings of the …, 2024 - pnas.org
Chimeric antigen receptor T cell therapies have achieved great success in eradicating some
liquid tumors, whereas the preclinical results in treating solid tumors have proven less …
liquid tumors, whereas the preclinical results in treating solid tumors have proven less …
Circulating immunotherapy strategy based on pyroptosis and STING pathway: Mn-loaded paclitaxel prodrug nanoplatform against tumor progression and metastasis
B Wang, T Wang, T Jiang, S Li, L Zhang, X Zhao… - Biomaterials, 2024 - Elsevier
Immunotherapy has emerged as a promising strategy against tumors. However, its efficacy
is limited by low immunogenicity, poor antigen presentation, and inadequate lymphocyte …
is limited by low immunogenicity, poor antigen presentation, and inadequate lymphocyte …
Partitioned Microneedle Patch Based on NO Release and HSP Inhibition for mPTT/GT Combination Treatment of Melanoma
Y Dong, J Tao, B Wang, A Zhang, G **ang… - … Applied Materials & …, 2024 - ACS Publications
Photothermal therapy (PTT) shows promise in cancer treatments due to its good
spatiotemporal selectivity and minimal invasiveness. However, PTT has some problems …
spatiotemporal selectivity and minimal invasiveness. However, PTT has some problems …
Simultaneous Light-Triggered Release of Nitric Oxide and Carbon Monoxide from a Lipid-Coated Upconversion Nanosystem Inhibits Colon Tumor Growth
Gas therapy has gained noteworthy attention in biomedical research, with the rise of gas-
releasing molecules enhancing their therapeutic potential, especially when integrated into …
releasing molecules enhancing their therapeutic potential, especially when integrated into …
Dual‐Modality Imaging‐Guided Manganese‐Based Nanotransformer for Enhanced Gas‐Photothermal Therapy Combined Immunotherapeutic Strategy Against Triple …
X Guan, N Zeng, Y Zhao, X Huang, S Lai, G Shen… - Small, 2024 - Wiley Online Library
Activating the stimulator of the interferon gene (STING) is a promising immunotherapeutic
strategy for converting “cold” tumor microenvironment into “hot” one to achieve better …
strategy for converting “cold” tumor microenvironment into “hot” one to achieve better …
A NRF2 Regulated and the Immunosuppressive Microenvironment Reversed Nanoplatform for Cholangiocarcinoma Photodynamic‐Gas Therapy
W Wang, Y Gao, J Xu, T Zou, B Yang, S Hu… - Advanced …, 2024 - Wiley Online Library
Photodynamic therapy (PDT) is a minimally invasive and controllable local cancer treatment
for cholangiocarcinoma (CCA). However, the efficacy of PDT is hindered by intratumoral …
for cholangiocarcinoma (CCA). However, the efficacy of PDT is hindered by intratumoral …
“Three‐in‐one”: A Photoactivable Nanoplatform Evokes Anti‐Immune Response by Inhibiting BRD4‐cMYC‐PDL1 Axis to Intensify Photo‐Immunotherapy
Combinatorial immuno‐cancer therapy is recognized as a promising approach for efficiently
treating malignant tumors. Yet, the development of multifunctional nanomedicine capable of …
treating malignant tumors. Yet, the development of multifunctional nanomedicine capable of …
Review of NIR-responsive ''Smart''carriers for photothermal chemotherapy
This review focuses on the versatile applications of near-infrared (NIR)-responsive smart
carriers in biomedical applications, particularly drug delivery and photothermal …
carriers in biomedical applications, particularly drug delivery and photothermal …