Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: from mechanism to therapy

J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …

[HTML][HTML] Chitosan–An alternative drug delivery approach for neurodegenerative diseases

M Iyer, A Elangovan, R Sennimalai, HWS Babu… - Carbohydrate Polymer …, 2024 - Elsevier
Neurological disorders have become severe and dreadful issues around the globe that are
rarely directly mediated because of the blood-brain barrier (BBB). Despite the various …

Tissue adhesive, biocompatible, antioxidant, and antibacterial hydrogels based on tannic acid and fungal-derived carboxymethyl chitosan for wound-dressing …

KM Rao, UT Uthappa, HJ Kim, SS Han - Gels, 2023 - mdpi.com
This study aimed to develop hydrogels for tissue adhesion that are biocompatible,
antioxidant, and antibacterial. We achieved this by using tannic acid (TA) and fungal-derived …

The preventive effects of Saccharomyces boulardii against oxidative stress induced by lipopolysaccharide in rat brain

F Babaei, A Navidi-Moghaddam, A Naderi… - Heliyon, 2024 - cell.com
The brain is sensitive to oxidative stress, which can trigger microglial activation and
neuroinflammation. Antioxidant therapies may provide neuroprotection against oxidative …

A TNF-α inhibitor abolishes sepsis-induced cognitive impairment in mice by modulating acetylcholine and nitric oxide homeostasis, BDNF release, and …

M Öz, H Erdal - Behavioural Brain Research, 2024 - Elsevier
Neurodegenerative disorders have a pathophysiology that heavily involves
neuroinflammation. In this study, we used lipopolysaccharide (LPS) to create a model of …

A novel Mediterranean diet-inspired supplement ameliorates cognitive, microbial, and metabolic deficits in a mouse model of low-grade inflammation

MG Pontifex, E Connell, G Le Gall, L Lang… - Gut …, 2024 - Taylor & Francis
The Mediterranean diet (MD) and its bioactive constituents have been advocated for their
neuroprotective properties along with their capacity to affect gut microbiota speciation and …

Sodium nitroprusside restored lipopolysaccharide‐induced learning and memory impairment in male rats via attenuating inflammation and oxidative stress

Z Hosseini, F Beheshti, FS Hosseini Kakhki… - Physiological …, 2024 - Wiley Online Library
Inflammation and oxidative stress upset memory. We explored influence of sodium
nitroprusside (SNP) on memory deficits resulted from lipopolysaccharide (LPS). Groups …

Effect of quercetin-loaded poly (lactic-co-glycolic) acid nanoparticles on lipopolysaccharide-induced memory decline, oxidative stress, amyloidogenesis …

RM Hussein, MA Kandeil, HM Soliman… - Heliyon, 2024 - cell.com
Neuroinflammation contributes to the pathogenesis of several neurodegenerative disorders.
This study examined the neuroprotective effect of quercetin (QUR)-loaded poly (lactic-co …

Blocking the major inflammatory pathways by newly synthesized thiadiazine derivatives via in-vivo, in-vitro and in-silico mechanism

SH Ullah, A Khan, SA Halim, R Khan, XD Pan… - Bioorganic …, 2023 - Elsevier
A series of new thiadiazine derivatives including 2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-
3-yl) propanoic acids (a) and 4-methyl-2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-3-yl) …

Beneficial effect of lupeol and metformin in mouse model of intracerebroventricular streptozotocin induced dementia

K Ram, K Kumar, D Singh, D Chopra, V Mani… - Metabolic Brain …, 2024 - Springer
This study examines the effectiveness of lupeol and metformin in a mouse model of
dementia generated by intracerebroventricular streptozotocin (icv, STZ). Dementia was …