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Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: from mechanism to therapy
J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …
of inflammatory responses is associated with most human diseases. Reactive oxygen …
[HTML][HTML] Chitosan–An alternative drug delivery approach for neurodegenerative diseases
M Iyer, A Elangovan, R Sennimalai, HWS Babu… - Carbohydrate Polymer …, 2024 - Elsevier
Neurological disorders have become severe and dreadful issues around the globe that are
rarely directly mediated because of the blood-brain barrier (BBB). Despite the various …
rarely directly mediated because of the blood-brain barrier (BBB). Despite the various …
Tissue adhesive, biocompatible, antioxidant, and antibacterial hydrogels based on tannic acid and fungal-derived carboxymethyl chitosan for wound-dressing …
This study aimed to develop hydrogels for tissue adhesion that are biocompatible,
antioxidant, and antibacterial. We achieved this by using tannic acid (TA) and fungal-derived …
antioxidant, and antibacterial. We achieved this by using tannic acid (TA) and fungal-derived …
The preventive effects of Saccharomyces boulardii against oxidative stress induced by lipopolysaccharide in rat brain
F Babaei, A Navidi-Moghaddam, A Naderi… - Heliyon, 2024 - cell.com
The brain is sensitive to oxidative stress, which can trigger microglial activation and
neuroinflammation. Antioxidant therapies may provide neuroprotection against oxidative …
neuroinflammation. Antioxidant therapies may provide neuroprotection against oxidative …
A TNF-α inhibitor abolishes sepsis-induced cognitive impairment in mice by modulating acetylcholine and nitric oxide homeostasis, BDNF release, and …
Neurodegenerative disorders have a pathophysiology that heavily involves
neuroinflammation. In this study, we used lipopolysaccharide (LPS) to create a model of …
neuroinflammation. In this study, we used lipopolysaccharide (LPS) to create a model of …
A novel Mediterranean diet-inspired supplement ameliorates cognitive, microbial, and metabolic deficits in a mouse model of low-grade inflammation
The Mediterranean diet (MD) and its bioactive constituents have been advocated for their
neuroprotective properties along with their capacity to affect gut microbiota speciation and …
neuroprotective properties along with their capacity to affect gut microbiota speciation and …
Sodium nitroprusside restored lipopolysaccharide‐induced learning and memory impairment in male rats via attenuating inflammation and oxidative stress
Z Hosseini, F Beheshti, FS Hosseini Kakhki… - Physiological …, 2024 - Wiley Online Library
Inflammation and oxidative stress upset memory. We explored influence of sodium
nitroprusside (SNP) on memory deficits resulted from lipopolysaccharide (LPS). Groups …
nitroprusside (SNP) on memory deficits resulted from lipopolysaccharide (LPS). Groups …
Effect of quercetin-loaded poly (lactic-co-glycolic) acid nanoparticles on lipopolysaccharide-induced memory decline, oxidative stress, amyloidogenesis …
RM Hussein, MA Kandeil, HM Soliman… - Heliyon, 2024 - cell.com
Neuroinflammation contributes to the pathogenesis of several neurodegenerative disorders.
This study examined the neuroprotective effect of quercetin (QUR)-loaded poly (lactic-co …
This study examined the neuroprotective effect of quercetin (QUR)-loaded poly (lactic-co …
Blocking the major inflammatory pathways by newly synthesized thiadiazine derivatives via in-vivo, in-vitro and in-silico mechanism
A series of new thiadiazine derivatives including 2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-
3-yl) propanoic acids (a) and 4-methyl-2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-3-yl) …
3-yl) propanoic acids (a) and 4-methyl-2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-3-yl) …
Beneficial effect of lupeol and metformin in mouse model of intracerebroventricular streptozotocin induced dementia
This study examines the effectiveness of lupeol and metformin in a mouse model of
dementia generated by intracerebroventricular streptozotocin (icv, STZ). Dementia was …
dementia generated by intracerebroventricular streptozotocin (icv, STZ). Dementia was …