Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most formidable challenge to …

In December 2019, a novel coronavirus was isolated from the respiratory epithelium of
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …

Background The diagnostic challenges associated with the COVID‐19 pandemic resulted in
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. Serology …

Humoral immune responses are typically characterized by primary IgM antibody responses
followed by secondary antibody responses associated with immune memory and composed …

Immune responses at the respiratory mucosal interface are critical to prevent respiratory
infections but it is unclear to what extent antigen specific mucosal secretory IgA (SIgA) …

Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes
coronavirus disease 2019 (COVID-19), primarily infects cells at mucosal surfaces. Serum …

To understand how a protective immune response against SARS-CoV-2 develops over time,
we integrated phenotypic, transcriptional, and repertoire analyses on PBMCs from patients …

Background Whereas severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-
specific antibody tests are increasingly being used to estimate the prevalence of SARS-CoV …

Respiratory mucosal immunity induced by vaccination is vital for protection from coronavirus
infection in animal models. In humans, the capacity of peripheral vaccination to generate …