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Role of monoamine oxidase activity in Alzheimer's disease: an insight into the therapeutic potential of inhibitors
T Behl, D Kaur, A Sehgal, S Singh, N Sharma… - Molecules, 2021 - mdpi.com
Despite not being utilized as considerably as other antidepressants in the therapy of
depression, the monoamine oxidase inhibitors (MAOIs) proceed to hold a place in …
depression, the monoamine oxidase inhibitors (MAOIs) proceed to hold a place in …
A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review
Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …
Recent progress in chemosensors based on pyrazole derivatives
Colorimetric and fluorescent probes based on small organic molecules have become
important tools in modern biology because they provide dynamic information concerning the …
important tools in modern biology because they provide dynamic information concerning the …
Monoamine oxidases (MAOs) as privileged molecular targets in neuroscience: research literature analysis
Background: Monoamine oxidases (MAOs) were discovered nearly a century ago. This
article aims to analyze the research literature landscape associated with MAOs as privileged …
article aims to analyze the research literature landscape associated with MAOs as privileged …
Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors
In the last years the continuous efforts in the development of novel and effective inhibitors of
human monoamine oxidases (hMAOs) promoted the discovery of new agents able to …
human monoamine oxidases (hMAOs) promoted the discovery of new agents able to …
Monoamine oxidase inhibitors: A concise review with special emphasis on structure activity relationship studies
Monoamine oxidase enzyme is necessary for the management of brain functions. It
oxidatively metabolizes monoamines and produces ammonia, aldehyde and hydrogen …
oxidatively metabolizes monoamines and produces ammonia, aldehyde and hydrogen …
Monoamine oxidase B inhibitors based on natural privileged scaffolds: A review of systematically structural modification
Y Lv, Z Zheng, R Liu, J Guo, C Zhang, Y **e - International Journal of …, 2023 - Elsevier
Monoamine oxidase is a flavin enzyme that catalyzes the oxidation of monoamine
neurotransmitters in the brain. Various toxic by-products, aldehydes and hydrogen peroxide …
neurotransmitters in the brain. Various toxic by-products, aldehydes and hydrogen peroxide …
Design, Synthesis, and Pharmacological Evaluation of N-Propargylated Diphenylpyrimidines as Multitarget Directed Ligands for the Treatment of Alzheimer's Disease
Alzheimer's disease (AD), a multifactorial complex neural disorder, is categorized with
progressive memory loss and cognitive impairment as main clinical features. The multitarget …
progressive memory loss and cognitive impairment as main clinical features. The multitarget …
Dual-Target Inhibitors Based on Acetylcholinesterase: Novel Agents for Alzheimer's Disease
X Zhao, Q Hu, X Wang, C Li, X Chen, D Zhao… - European Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia among the elderly,
accounting for 60% to 70% of cases. At present, the pathogenesis of this condition remains …
accounting for 60% to 70% of cases. At present, the pathogenesis of this condition remains …
Piperazine, a Key Substructure for Antidepressants: Its Role in Developments and Structure‐Activity Relationships
Depression is the single largest contributor to global disability with a huge economic and
social burden on the world. There are a number of antidepressant drugs on the market, but …
social burden on the world. There are a number of antidepressant drugs on the market, but …