Helminth endemic regions report lower COVID-19 morbidity and mortality. Here, we show
that lung remodeling from a prior infection with a lung-migrating helminth, Nippostrongylus …

Viral infections are often studied in model mammalian organisms under specific pathogen-
free conditions. However, in nature, coinfections are common, and infection with one …

Different human and animal pathogens trigger distinct immune responses in their hosts. The
infection of bacteria or viruses can trigger type I pro-inflammatory immune responses (eg …

Genital herpes is characterized by recurrent episodes of epithelial blistering. The
mechanisms causing this pathology are ill defined. Using a mouse model of vaginal herpes …

IL-33 is an alarmin cytokine which has been implicated in allergy, fibrosis, inflammation,
tumorigenesis, metabolism, and homeostasis. However, amongst its strongest roles are in …

In recent years, there has been ample evidence illustrating the effect of microbiota on gut
immunity, homeostasis, and disease. Most of these studies have engaged more efforts in …

Gastrointestinal nematode (GIN) infection has applied significant evolutionary pressure to
the mammalian immune system and remains a global economic and human health burden …

Helminths are parasitic worms that coevolve with their host, usually resulting in long-term
persistence through modulating host immunity. The multifarious mechanisms altering the …

Soil-transmitted helminths affect approximately 1.5 billion people worldwide. However, as no
vaccine is currently available for humans, the current strategy for elimination as a public …

The most important soil-transmitted helminths (STHs) affecting humans are roundworms,
whipworms, and hookworms, with a large proportion of the world's population infected with …