A guide to human zinc absorption: general overview and recent advances of in vitro intestinal models

M Maares, H Haase - Nutrients, 2020 - mdpi.com
Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic
homeostasis of this essential trace element. This review summarizes the key aspects of …

Zinc and immunity: An essential interrelation

M Maares, H Haase - Archives of biochemistry and biophysics, 2016 - Elsevier
The significance of the essential trace element zinc for immune function has been known for
several decades. Zinc deficiency affects immune cells, resulting in altered host defense …

Zinc in human health and infectious diseases

M Maywald, L Rink - Biomolecules, 2022 - mdpi.com
During the last few decades, the micronutrient zinc has proven to be an important metal ion
for a well-functioning immune system, and thus also for a suitable immune defense …

The role of Fe, Zn, and Cu in pregnancy

K Grzeszczak, S Kwiatkowski, D Kosik-Bogacka - Biomolecules, 2020 - mdpi.com
Iron (Fe), copper (Cu), and zinc (Zn) are microelements essential for the proper functioning
of living organisms. These elements participatein many processes, including cellular …

Role of zinc in female reproduction

TB Garner, JM Hester, A Carothers… - Biology of …, 2021 - academic.oup.com
Zinc is a critical component in a number of conserved processes that regulate female germ
cell growth, fertility, and pregnancy. During follicle development, a sufficient intracellular …

Analysis and update of the human solute carrier (SLC) gene superfamily

L He, K Vasiliou, DW Nebert - Human genomics, 2009 - Springer
The solute-carrier gene (SLC) superfamily encodes membrane-bound transporters. The
SLC superfamily comprises 55 gene families having at least 362 putatively functional protein …

Role of zinc in neonatal growth and brain growth: review and sco** review

LP Brion, R Heyne, CS Lair - Pediatric Research, 2021 - nature.com
This manuscript includes (1) a narrative review of Zinc as an essential nutrient for fetal and
neonatal growth and brain growth and development and (2) a sco** review of studies …

Appropriate nutrient supplementation in celiac disease

R Caruso, F Pallone, E Stasi, S Romeo… - Annals of …, 2013 - Taylor & Francis
Reduced levels of iron, folate, vitamin B12, vitamin D, zinc, and magnesium are common in
untreated celiac disease (CD) patients probably due to loss of brush border proteins and …

A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity

J Geiser, KJT Venken, RC De Lisle, GK Andrews - PLoS genetics, 2012 - journals.plos.org
Mutations in the human Zip4 gene cause acrodermatitis enteropathica, a rare, pseudo-
dominant, lethal genetic disorder. We created a tamoxifen-inducible, enterocyte-specific …

Structure, properties, and engineering of the major zinc binding site on human albumin

CA Blindauer, I Harvey, KE Bunyan, AJ Stewart… - Journal of Biological …, 2009 - ASBMB
Most blood plasma zinc is bound to albumin, but the structure of the binding site has not
been determined. Zn K-edge extended x-ray absorption fine structure spectroscopy and …