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The immunology of Epstein-Barr virus–induced disease
Epstein-Barr virus (EBV) is usually acquired silently early in life and carried thereafter as an
asymptomatic infection of the B lymphoid system. However, many circumstances disturb the …
asymptomatic infection of the B lymphoid system. However, many circumstances disturb the …
The tumour microenvironment in B cell lymphomas
B cell lymphomas are cancers that arise from cells that depend on numerous highly
orchestrated interactions with immune and stromal cells in the course of normal …
orchestrated interactions with immune and stromal cells in the course of normal …
Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
Background Despite advances in treatments for Hodgkin's lymphoma, about 20% of patients
still die from progressive disease. Current prognostic models predict the outcome of …
still die from progressive disease. Current prognostic models predict the outcome of …
Phase II investigator-initiated study of brentuximab vedotin in mycosis fungoides and Sézary syndrome with variable CD30 expression level: a multi-institution …
YH Kim, M Tavallaee, U Sundram, KA Salva… - Journal of Clinical …, 2015 - ascopubs.org
Purpose In contrast to Hodgkin lymphoma and systemic anaplastic large-cell lymphoma,
CD30 expression of malignant lymphocytes in mycosis fungoides (MF) and Sézary …
CD30 expression of malignant lymphocytes in mycosis fungoides (MF) and Sézary …
Hodgkin lymphoma
Hodgkin lymphoma (HL) is a B cell lymphoma characterized by few malignant cells and
numerous immune effector cells in the tumour microenvironment. The incidence of HL is …
numerous immune effector cells in the tumour microenvironment. The incidence of HL is …
Molecular pathogenesis of Hodgkin's lymphoma: increasing evidence of the importance of the microenvironment
Hodgkin's lymphoma (HL) represents the most common subtype of malignant lymphoma in
young people in the Western world. Most patients can be cured with modern treatment …
young people in the Western world. Most patients can be cured with modern treatment …
Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors
Background Tumor-infiltrating T cells are associated with survival in epithelial ovarian
cancer (EOC), but their functional status is poorly understood, especially relative to the …
cancer (EOC), but their functional status is poorly understood, especially relative to the …
Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review
R Camicia, HC Winkler, PO Hassa - Molecular cancer, 2015 - Springer
Diffuse large B-cell lymphoma (DLBCL) is a clinically heterogeneous lymphoid malignancy
and the most common subtype of non-Hodgkin's lymphoma in adults, with one of the highest …
and the most common subtype of non-Hodgkin's lymphoma in adults, with one of the highest …
The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape
D Aldinucci, A Gloghini, A Pinto… - The Journal of …, 2010 - Wiley Online Library
It has become clear that cancer is not merely a growth of autonomously proliferating cells,
but that other non‐malignant cell types are a functional part of the disease. Immune cells …
but that other non‐malignant cell types are a functional part of the disease. Immune cells …
Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial
Increased tumor-associated macrophages (TAMs) are reported to be associated with poor
prognosis in classic Hodgkin lymphoma (CHL). We investigated the prognostic significance …
prognosis in classic Hodgkin lymphoma (CHL). We investigated the prognostic significance …