Hepatocellular carcinoma (HCC) is an aggressive human cancer with increasing incidence
worldwide. Multiple efforts have been made to explore pharmaceutical therapies to treat …

Cancer cells often encounter hypoxic and hypo-nutrient conditions, which force them to
make adaptive changes to meet their high demands for energy and various biomaterials for …

Hepatocellular carcinoma (HCC) is an inflammation-induced and chemotherapy-resistant
cancer. Dysregulated signaling in the transforming growth factor beta (TGF-β) pathway plays …

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, with high
incidence and mortality, accounting for approximately 90% of liver cancer. The development …

Primary liver cancer (PLC) is the fourth most frequent cause of cancer-related death. The
high mortality rates arise from late diagnosis and the limited accuracy of diagnostic and …

Acylcarnitines play an essential role in regulating the balance of intracellular sugar and lipid
metabolism. They serve as carriers to transport activated long-chain fatty acids into …

Metabolic reprogramming for adaptation to the local environment has been recognized as a
hallmark of cancer. Although alterations in fatty acid (FA) metabolism in cancer cells have …

Metabolic alteration for adaptation of the local environment has been recognized as a
hallmark of cancer. GNPAT dysregulation has been implicated in hepatocellular carcinoma …

In this research, a novel polysaccharide (PCP) was extracted from Pleurotus citrinopileatus
and purified by Sephadex G-150 gel column, and its antitumor activity was investigated …

Metabolic reprogramming is often observed in carcinogenesis, but little is known about the
aberrant metabolic genes involved in the tumorigenicity and maintenance of stemness in …