[HTML][HTML] Immune checkpoints between epithelial-mesenchymal transition and autophagy: a conflicting triangle

M Cordani, R Strippoli, F Trionfetti, AB Behrooz… - Cancer Letters, 2024 - Elsevier
Inhibitory immune checkpoint (ICP) molecules are pivotal in inhibiting innate and acquired
antitumor immune responses, a mechanism frequently exploited by cancer cells to evade …

Cardiotoxicity of novel targeted hematological therapies

V Giudice, C Vecchione, C Selleri - Life, 2020 - mdpi.com
Chemotherapy-related cardiac dysfunction, also known as cardiotoxicity, is a group of drug-
related adverse events negatively affecting myocardial structure and functions in patients …

Association between germ-line HLA and immune-related adverse events

N Jiang, Y Yu, M Zhang, Y Tang, D Wu… - Frontiers in …, 2022 - frontiersin.org
Background In recent years, significant progress has been made in immune checkpoint
inhibitors (ICIs). However, accompanied by remarkable efficacy, a growing number of …

Epstein-Barr virus BART microRNAs in EBV-associated Hodgkin lymphoma and gastric cancer

V De Re, L Caggiari, M De Zorzi, V Fanotto… - Infectious agents and …, 2020 - Springer
Background EBV produces miRNAs with important functions in cancer growth, tumor
invasion and host immune surveillance. The discovery of EBV miR-BARTs is recent, and …

Enhanced PD-L1 Expression in LMP1-positive Cells of Epstein-Barr Virus–associated Malignant Lymphomas and Lymphoproliferative Disorders: A Single-cell …

A Kume, A Shinozaki-Ushiku, A Kunita… - The American Journal …, 2022 - journals.lww.com
Epstein-Barr virus (EBV) is associated with various types of human malignancies and with
programmed death ligand (PD-L) 1 expression in neoplastic cells. However, in EBV …

Overview of epstein–barr-virus-associated gastric cancer correlated with prognostic classification and development of therapeutic options

V De Re, G Brisotto, O Repetto, M De Zorzi… - International Journal of …, 2020 - mdpi.com
Gastric cancer (GC) is a deadly disease with poor prognosis that is characterized by
heterogeneity. New classifications based on histologic features, genotypes, and molecular …

Metabolic reprogramming of the tumor microenvironment to enhance immunotherapy

SA Lim - BMB reports, 2024 - pmc.ncbi.nlm.nih.gov
Immunotherapy represents a promising treatment strategy for targeting various tumor types.
However, the overall response rate is low due to the tumor microenvironment (TME). In the …

Proteomic and phospholipidomic characterization of extracellular vesicles inducing tumor microenvironment in Epstein‐Barr virus‐associated lymphomas

M Ito, K Kudo, H Higuchi, H Otsuka… - The FASEB …, 2021 - Wiley Online Library
Epstein‐Barr virus (EBV) causes malignant carcinomas including B cell lymphomas
accompanied by the systemic inflammation. Previously, we observed that …

[HTML][HTML] Understanding the effects of radiotherapy on the tumour immune microenvironment to identify potential prognostic and predictive biomarkers of radiotherapy …

S Cheng, E J. Cheadle, T M. Illidge - Cancers, 2020 - mdpi.com
Simple Summary Around 50% of all cancer patients receive radiotherapy as part of their
treatment. Recently immunotherapy has shown promising results and become established …

Tumor-immune signatures of treatment resistance to brentuximab vedotin with ipilimumab and/or nivolumab in Hodgkin lymphoma

E Gonzalez-Kozlova, HH Huang… - Cancer research …, 2024 - aacrjournals.org
To investigate the cellular and molecular mechanisms associated with targeting CD30-
expressing Hodgkin lymphoma (HL) and immune checkpoint modulation induced by …