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A new era of antibiotics: the clinical potential of antimicrobial peptides
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …
Host control of the microbiome: mechanisms, evolution, and disease
Many species, including humans, host communities of symbiotic microbes. There is a vast
literature on the ways these microbiomes affect hosts, but here we argue for an increased …
literature on the ways these microbiomes affect hosts, but here we argue for an increased …
Antimicrobial peptides: Application informed by evolution
BACKGROUND Antimicrobial peptides (AMPs) are small proteins with potent antibacterial,
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …
Host specificity of the gut microbiome
Develo** general principles of host–microorganism interactions necessitates a robust
understanding of the eco-evolutionary processes that structure microbiota. Phylosymbiosis …
understanding of the eco-evolutionary processes that structure microbiota. Phylosymbiosis …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
Phylosymbiosis: relationships and functional effects of microbial communities across host evolutionary history
Phylosymbiosis was recently proposed to describe the eco-evolutionary pattern, whereby
the ecological relatedness of host-associated microbial communities parallels the phylogeny …
the ecological relatedness of host-associated microbial communities parallels the phylogeny …
Interplay between innate immunity and the plant microbiota
The innate immune system of plants recognizes microbial pathogens and terminates their
growth. However, recent findings suggest that at least one layer of this system is also …
growth. However, recent findings suggest that at least one layer of this system is also …
Microbiota and host nutrition across plant and animal kingdoms
Plants and animals each have evolved specialized organs dedicated to nutrient acquisition,
and these harbor specific bacterial communities that extend the host's metabolic repertoire …
and these harbor specific bacterial communities that extend the host's metabolic repertoire …
Simple animal models for microbiome research
AE Douglas - Nature Reviews Microbiology, 2019 - nature.com
The health and fitness of animals, including humans, are influenced by the presence and
composition of resident microbial communities. The development of rational microbial …
composition of resident microbial communities. The development of rational microbial …
Microbiota mediated plasticity promotes thermal adaptation in the sea anemone Nematostella vectensis
At the current rate of climate change, it is unlikely that multicellular organisms will be able to
adapt to changing environmental conditions through genetic recombination and natural …
adapt to changing environmental conditions through genetic recombination and natural …